دانلود مقالات ISI درباره 5-FU، 5-fluorouracil + ترجمه فارسی

تعیین همزمان کپسیباتین و متابولیت های نوکلئیدی آن در پلاسمای انسان با استفاده از کروماتوگرافی مایع با عملکرد بالا طیف سنجی جرمی

Simultaneous determination of capecitabine and its three nucleoside metabolites in human plasma by high performance liquid chromatography–tandem mass spectrometry

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; Cape, capecitabine; DFCR, 5′-deoxy-5-fluorocytidine; DFUR, 5′-deoxy-5-fluorouridine; EMA, European Medicines Agency; FDA, Food and Drug Administration; HQC, high quality control; IS, internal standard; LLOQ, lower limit of quantifica

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

تأثیر درازمدت شیمی درمانی اگزال پلاتین بر شناخت جوندگان و نوروپاتی محیطی

The long-term impact of oxaliplatin chemotherapy on rodent cognition and peripheral neuropathy

Keywords: 5-FU، 5-fluorouracil; Oxaliplatin; Chemotherapy; Cognition; Rat; Peripheral neuropathy; Mechanical allodyniaCNS, Central nervous system; OX, Oxaliplatin; NOR, Novel object recognition; NLR, Novel location recognition; 5-FU, 5-fluorouracil

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

نانوذرات پروبیوتیک لیپید در درمان سرطان

Lipid prodrug nanocarriers in cancer therapy

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; ara-C, cytosine arabinoside; AUC, area under the curve, chol, cholesterol; CLA, conjugated linoleic acid; BLI, bioluminescence imaging; dCK, deoxycitydine kinase; dCK, deoxycitydine kinase; dFdU, difluorodeoxyuridine; DNA, deoxyribon

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

رسکوراترول موجب شبیه سازی حساسیت به 5-فلوئوروآاروسیل می شود از طریق تنظیم مقاطع بین سلولی، انتقال پروتئین به مزانشیمال و آپوپتوز در سرطان کولورکتال

Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer

Keywords: 5-FU، 5-fluorouracil; AT, ambient temperature; BSA, bovine serum albumin; CRC, colorectal cancer; DMEM, Dulbecco’s modified Eagle’s medium; EMT, epithelial-mesenchymal transition; FBS, fetal bovine serum; IKK, IκB kinase; 5-FU, 5-Fluorouracil; MMP, matrix metalloproteinase; MT

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

پلیمورفیسم ژن های مرتبط با متابولیسم فولات و بقای بیماران مبتلا به سرطان کولورکتال در جمعیت کره ای

Polymorphisms of folate metabolism-related genes and survival of patients with colorectal cancer in the Korean population

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; CRC, colorectal cancer; TS, thymidylate synthase; TSER, thymidylate synthase enhancer region; MTHFR, methylenetetrahydrofolate reductase; RFC1, reduced folate carrier 1; OS, overall survival; RFS, relapse-free survival; HR, hazard ra

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

پروتئین 3 مرتبط با مقاومت چند دارویی مقاومت 3 به شیمی درمانی برای سرطان رکتوم را با تنظیم گونه های اکسیژن واکنشی و مسیر آپوپتوز وابسته به کاسپاز 3

Multidrug resistance-associated protein 3 confers resistance to chemoradiotherapy for rectal cancer by regulating reactive oxygen species and caspase-3-dependent apoptotic pathway

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; APR, abdominoperineal resection; CA19-9, carbohydrate antigen 19-9; CCK-8, cell counting kit-8; CEA, carcinoembryonic antigen; CI, confidence interval; DCF, 2′, 7′-dichlorofluorescein; DCFH-DA, 2′,7′-dichlorofluorescein diacetate; DF

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

تفاوت های جنسیتی در سیستم های زمانبندی روزانه: پیامدهای بیماری

Sex differences in circadian timing systems: Implications for disease

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; 5-HT, serotonergic; E2, 17β-estradiol; ACTH, adrenocorticotropic hormone; AMY, amygdala; ANS, autonomic nervous system; AP, action potential; AR, androgen receptors; ARC, arcuate nucleus; AVP, arginine vasopressin; AVPV, anterolatera

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2014 سفارش ترجمه

استرس شبکه آندوپلاسمی باعث مقاومت 5-فلوئورواوراسیل در سلول های سرطانی روده بزرگ انسان

Endoplasmic reticulum stress induces 5-fluorouracil resistance in human colon cancer cells

Keywords: 5-FU، 5-fluorouracil; AKT, protein kinase B; AM, acetoxymethyl ester; ATF6, activating transcription factor 6; CHOP, C/EBP homologous protein; eIF2, eukaryotic initiation factor 2; ER, endoplasmic reticulum; ERK, extracellular signal-regulated kinase; 5-FU, 5-fluorouracil; GRP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

نظارت بر سمیت ژنی در بیماران تحت شیمی درمانی برای سرطان: استفاده از سنجش PIG-A

Monitoring genotoxicity in patients receiving chemotherapy for cancer: application of the PIG-A assay

Keywords: 5-FU، 5-fluorouracil; CDHP, 5 chloro-2,4-dihydroxypyridine; 5-FU, 5-fluorouracil; %RET, percentage of reticulocytes; FITC, fluorescein isothiocyanate; GEM, gemcitabine; GPI, glycosylphosphatidylinositol; MF, mutant frequency; Oxo, monopotassium 1,2,3,4-tetrahydro-2,4-dioxo-1,3

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Wheat bran arabinoxylan supplementation alleviates 5-fluorouracil induced mucositis and myelosuppression in BALB/c mice

Keywords: 5-FU، 5-fluorouracil; AX, rabinoxylan; 5-FU, 5-fluorouracil; PCNA, proliferating cell nuclear antigenArabinoxylan; Mucositis; Myelosuppression; 5-fluorouracil; Chemotherapy5-fluouracil (PubChem CID: 3385); Chloroform (PubChem CID: 6212); Diethylpyrocarbonate (PubChem CID: 3051

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Macrophages induce resistance to 5-fluorouracil chemotherapy in colorectal cancer through the release of putrescine

Keywords: 5-FU، 5-fluorouracil; Colorectal cancer; Chemoresistance; Macrophage; Putrescine; ApoptosisTAM, tumor associated macrophage; 5-FU, 5-fluorouracil; CRC, colorectal cancer; ODC, ornithine decarboxylase; DMEM, Dulbecco modified Eagle's medium; FACS, fluorescence-activated cell so

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

pH and redox-operated nanovalve for size-selective cargo delivery on hollow mesoporous silica spheres

Keywords: 5-FU، 5-fluorouracil; β-CD, β-cyclodextrins; HMSs, hollow mesoporous silica nanoparticles; Fc, ferrocenyl moiety; NHS, N-hydroxysuccinimide; EDC, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide-HCl; R6G, Rhodamine 6G; DOX, doxorubicin hydrochloride; 5-FU, 5-fluorouracil; MSNs, m

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Lipopolysaccharide supports maintaining the stemness of CD133+ hepatoma cells through activation of the NF-κB/HIF-1α pathway

Keywords: 5-FU، 5-fluorouracil; HCC, hepatocellular carcinoma; CSCs, cancer stem cells; TICs, tumor initiating cells; LPS, lipopolysaccharide; EMT, epithelial–mesenchymal transition; FBS, fetal bovine serum; 5-Fu, 5-fluorouracil; TLR4, toll-like receptor 4; PAMPs, pathogen-associated mo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Silencing of CD59 enhanced the sensitivity of HT29 cells to 5-Fluorouracil and Oxaliplatin

Keywords: 5-FU، 5-fluorouracil; CD55; CD59; 5-Fluorouracil; Oxaliplatin; HT-29; Chemotherapy sensitivitymCRPs, membrane complement regulatory proteins; 5-FU, 5-Fluorouracil; SiRNA, small interfering RNA; MCP, membrane cofactor protein (CD46); MAC, membrane attack complex; DAF, decay-acc

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Autophagy contributes to the enrichment and survival of colorectal cancer stem cells under oxaliplatin treatment

Keywords: 5-FU، 5-fluorouracil; Colorectal cancer; Autophagy; Cancer stem cells; ChemoresistanceCRC, colorectal cancer; CSCs, cancer stem cells; 5-FU, 5-fluorouracil; OXA, oxaliplatin; H/S, hypoxia/starvation environment; 3-MA, 3-methyladenine; CQ, chloroquine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)-9H- or 7H-purines against several human solid tumour cell lines

Keywords: 5-FU، 5-fluorouracil; Anti-tumour compounds; Apoptosis; 5-Fluorouracil; Breast cancer; Colon cancer; Melanoma; PurinesDCA, Dichloroacetate; FACS, Flow cytometry; 5-FU, 5-Fluorouracil; MW, Microwave; SRB, Sulforhodamine-B

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Orai1 and STIM1 mediate SOCE and contribute to apoptotic resistance of pancreatic adenocarcinoma

Keywords: 5-FU، 5-fluorouracil; PDAC, pancreatic ductal adenocarcinoma; SOCE, store operated calcium entry; SOCs, store-operated calcium channels; STIM1, stromal interaction molecule 1; 5-FU, 5-Fluorouracil; TG, thapsigargin; SERCA, sarco/endoplasmic reticulum Ca2 + ATPase; siRNA, small

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Prognostic advantage of irinotecan dose escalation according to uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) genotyping in patients with metastatic colorectal cancer treated with bevacizumab combined with 5-fluorouracil/leucovorin with irinote

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; AE, adverse event; CRC, colorectal cancer; FOLFIRI, 5-fluorouracil/leucovorin with irinotecan; IV, intravenous; LV, leucovorin; mCRC, metastatic colorectal cancer; OS, overall survival; PCR, polymerase chain reaction; PFS, progressio

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and in vitro evaluation of bile acid prodrugs of floxuridine to target the liver

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; Boc2O, di-tert-butyl dicarbonate; CDCA, chenodeoxycholic acid; DCC, N,N′-dicyclohexylcarbodiimide; DCM, dichloromethane; DMAP, 4-dimethylaminopyridine; DMEM, Dulbecco’s modified Eagle medium; DMF, dimethyl formamide; DMSO, dimethyl s

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

γ-H2AX as a biomarker for DNA double-strand breaks in ecotoxicology

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; 53BP1, p53 binding protein 1; API, aphidicolin; ARA-C, cytarabine; ATM, ataxia telangiectasia mutated; ATR, ataxia telangiectasia related; BLAP, ß-lapachone; BLM, bleomycin; BRCA1, breast cancer type 1 susceptibility protein; cDDP, c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis of platinum(II) complexes of isatin thiosemicarbazones derivatives: In vitro anti-cancer and deoxyribose nucleic acid binding activities

Keywords: 5-FU، 5-fluorouracil; CT DNA, calf-thymus DNA; DMSO, dimethyl sulfoxide; EB, ethidium bromide; 5-FU, 5-fluorouracil; UV–Vis, UV–visible; ROS, reactive oxygen speciesPlatinum(II) complexes; Isatin moiety; Intercalative activity; Anti-proliferative study

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of two novel functional p53 responsive elements in the herpes simplex virus-1 genome

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; ChIP, chromatin immunoprecipitation; EMSA, electrophoretic mobility shift assay; FBS, fetal bovine serum; HSV, herpes simplex virus; IE, immediate early; moi, multiplicity of infection; PBS, phosphate buffered saline; RE, responsive

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

In vitro combinatorial anticancer effects of 5-fluorouracil and curcumin loaded N,O-carboxymethyl chitosan nanoparticles toward colon cancer and in vivo pharmacokinetic studies

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; CUR, curcumin; N,O-CMC, N,O-carboxymethyl chitosan; FT-IR, Fourier transforms Infrared spectroscopy; DDA, degree of deacetylation; kDa, kilo Dalton; Mw, molecular weight; DLS, dynamic light scattering; PBS, phosphate buffered saline;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells

Keywords: 5-FU، 5-fluorouracil; CRC, colorectal carcinoma; 5-FU, 5-fluorouracil; UA, ursolic acid; MSI, microsatellite instability; JNK, c-jun N-terminal kinase; MAPK, mitogen-activated protein kinase; NAC, N-acetyl-l-cysteine; STS, staurosporine; TUNEL, TdT-mediated dUTP nick end label

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Antitumor effect of 5-fluorouracil is enhanced by rosemary extract in both drug sensitive and resistant colon cancer cells

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; CI, combination index; MTT, thiazolyl blue tetrazolium bromide; RT-PCR, real-time polymerase chain reaction; SFRE, supercritical fluid rosemary extract; SW620-5FU-R, human colon cancer SW620 cells resistant to 5-fluorouracil5-Fluorou

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Attenuation of nucleoside and anti-cancer nucleoside analog drug uptake in prostate cancer cells by Cimicifuga racemosa extract BNO-1055

Keywords: 5-FU، 5-fluorouracil; BCa, breast cancer; BrdU, 5-bromo-2′-deoxyuridine; CNT, concentrative nucleoside transporter; CR, cimicifuga racemosa; ENT, equilibrative nucleoside transporter; 5-FU, 5-fluorouracil; HPLC, high-pressure liquid chromatography; NBTI, nitrobenzylthioinosine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Interactions between dietary flavonoids apigenin or luteolin and chemotherapeutic drugs to potentiate anti-proliferative effect on human pancreatic cancer cells, in vitro

Keywords: 5-FU، 5-fluorouracil; Api, -apigenin; Cis-, cisplatin; 5-FU, 5-fluorouracil; Gem-, gemcitabine; Oxa, -oxaliplatin; GSK-3β-, glycogen synthase kinase-3β; Lut-, luteolin; MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium; NF-κB, -nucle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Synergistic and individual effects of umbelliferone with 5-fluorouracil on tumor markers and antioxidant status of rat treated with 1,2-dimethylhydrazine

Keywords: 5-FU، 5-fluorouracil; Colon cancer; Complementary medicines; Umbelliferone; 5-fluorouracil; Lipid peroxidationCRC, Colorectal cancer; 5-FU, 5-fluorouracil; UMB, Umbelliferone; CEA, Carcinoembroyonic antigen; CA 19-9, Carbohydrate antigen 19-9; CA 72-4, Carbohydrate antigen 72-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting c-FLIP in cancer

Keywords: 5-FU، 5-fluorouracil; c-FLIP; Death receptors; CancerCDDP, cisplatin; VP16, etoposide; 5-FU, 5-fluorouracil; DISC, death-inducing signaling complex; DcR2, TRAIL-R4 or decoy receptor 2; DR5, TRAIL-R1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Therapeutic Advances in Pancreatic Cancer

Keywords: 5-FU، 5-fluorouracil; Pancreatic Cancer; Chemotherapy; Adjuvant TherapyESPAC, European Study Group for Pancreatic Cancer; 5-FU, 5-fluorouracil; hENT-1, human equilibrative nucleoside transporter 1; LDP, laparoscopic distal pancreatectomy; MDACC, MD Anderson Cancer Center; PDAC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Cancer stem cells: therapeutic implications and perspectives in cancer therapy

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; ABC, ATP-binding cassette; ABCB1, ATP binding cassette superfamily subfamily B member 1; ABCG2, ATP binding cassette superfamily subfamily G member 2; ALDH1, aldehyde dehydrogenase1; AML, acute myeloid leukemia; AMO, anti-miRNA oligo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Overview of the therapeutic potential of piplartine (piperlongumine)

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; AHNAK, neuroblast differentiation-associated protein; ALT, alanine amino transaminase; ANXA5, Annexin A5; AST, aspartate amino transferase; Bcl-2, B-cell leukemia/lymphoma 2; Bim, Bcl-2 interacting mediator of cell death; CBR1, carbo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

MBD4 and TDG: Multifaceted DNA glycosylases with ever expanding biological roles

Keywords: 5-FU، 5-fluorouracil; 5-BrU, 5-bromouracil; 5-ClU, 5-chlorouracil; 5-FU, 5-fluorouracil; 5-hmC, 5-hydroxymethylcytosine; 5-hmU, 5-hydroxymethyluracil; 5-IdU, 5-iododeoxyuridine; 5-meC, 5-methylcytosine; A, adenine; AID, activation-induced deaminase; Apc, adenomatous polyposis

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Selective sensitization of tumors to chemotherapy by marine-derived lipids: A review

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; CPK, creatine phosphokinase; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; FDA, food and drug administration; FEC, 5-fluorouracil epirubicin cyclophosphamide; FOLFIRI, 5-fluorouracil leucovorin irinotecan; FOLFOX, 5-fluorour

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Role of the RAD51 G172T polymorphism in the clinical outcome of cervical cancer patients under concomitant chemoradiotherapy

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; RCT, radiochemotherapy; HPV, Human papillomavirus; DSB, double-strand break(s); HR, homologous recombination; NHEJ, non-homologous recombination; kb, kilobase; UTR, untranslated region(s); SNP, single nucleotide polymorphism(s); MAF,

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of 5-fluorouracil and gemcitabine on a breast cancer cell line (MCF-7) via the JAK/STAT pathway

Keywords: 5-FU، 5-fluorouracil; ANOVA, analysis of variance; BclxL, B-cell lymphoma-extra large; DSMZ, Deutsche Sammlung von Mikroorganismen und Zellkulturen (German Collection of Microorganisms and Cell Cultures); 5 FdUMP, 5-fluorodeoxyuridine monophosphate; 5-FU, 5-fluorouracil; 5 FUT

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Synergistic anticancer effect of rAd/P53 combined with 5-fluorouracil or iodized oil in the early therapeutic response of human colon cancer in vivo

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; wt-p53, wild-type p53; rAd/p53, recombinant adenovirus-mediated p53; IACUC, Institutional Animal Care and Use Committee; HE, hematoxylin and eosin; ECL, enhanced chemiluminescence; KI, Ki-67 index; IOD, integrity optical density; RIO

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Development and utilization of a combined LC–UV and LC–MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; UFT®, uracil and tegafur; LV, leucovorin (folinic acid); PK, pharmacokinetic; AUC, area under the curve; RT, radiation therapy; HPLC, high performance liquid chromatography; MS/MS, tandem mass spectrometry; UV, ultraviolet spectrosco

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Expression and regulation of RAD51 mediate cellular responses to chemotherapeutics

Keywords: 5-FU، 5-fluorouracil; HR, homologous recombination; DSBs, DNA double strand breaks; TS, thymidylate synthase; RTX, raltitrexed (Tomudex™); 5-FU, 5-fluorouracil; FdUrd, fluorodeoxyuridine; UCN-01, 7-Hydroxy-staurosporine; GFP, green fluorescent proteinThymidylate synthase; Homo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

EUS or percutaneously guided intratumoral TNFerade biologic with 5-fluorouracil and radiotherapy for first-line treatment of locally advanced pancreatic cancer: a phase I/II study

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; ANC, absolute neutrophil count; CRT, chemoradiation therapy; DLT, dose-limiting toxicity; DVT, deep vein thrombosis; EUS-FNI, EUS-guided fine-needle viral injection; FNI, fine-needle viral injection; LAPC, locally advanced pancreatic

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Antitumor activity of Dioscorea bulbifera L. rhizome in vivo

Keywords: 5-FU، 5-fluorouracil; DB, Dioscorea bulbifera L.; fraction A, water extract; fraction B, ethanol extract; fraction C, ethyl acetate extract; fraction D, non-ethyl acetate extract; 5-Fu, 5-Fluorouracil; i.g., intragastric administration; CMC-Na, sodium carboxymethyl cellulose;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Anticancer activity of small amphipathic β2,2-amino acid derivatives

Keywords: 5-FU، 5-fluorouracil; Anticancer peptide; Antimicrobial peptide; Amphipathic scaffold; Beta-amino acid; PeptidomimeticsAMP, cationic antimicrobial peptide; BOC2O, di-tert-butyl dicarbonate; DIPEA, di-isopropyl ethyl amine; 5-FU, 5-fluorouracil; LfcinB, bovine lactoferricin; MB

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Up-regulation of FXR isoforms is not required for stimulation of the expression of genes involved in the lack of response of colon cancer to chemotherapy

Keywords: 5-FU، 5-fluorouracil; CDDP, cis-diamminedichloroplatinum(II); CRAC, colorectal adenocarcinoma; 5-FU, 5-fluorouracil; FXR, farnesoid X receptor; MDR, multidrug resistance; MOC, mechanism of chemoresistance; TKI, tyrosine kinase inhibitor; TLDA, Taqman Low-Density ArrayChemoresi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Local control of experimental malignant pancreatic tumors by treatment with a combination of chemotherapy and intratumoral 224Radium-loaded wires releasing alpha-emitting atoms

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; DaRT, diffusing alpha-emitters radiation therapy; DSB, double strand breaks; DMEM, Dulbecco's modified eagle medium; LET, linear energy transfer; OD, optical density; PBS, phosphate-buffered saline; SCC, squamous cell carcinoma; SSB,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Suicide gene therapy in cancer: Where do we stand now?

Keywords: 5-FU، 5-fluorouracil; AMSCs, adipose tissue mesenchymal stromal cells; CD, cytosine deaminase; CSCs, cancer stem cells; DOTAP, 1,2-dioleoyl-3-(trimethylammonium) propane; Chol, cholesterol; 5-FC, 5-fluorocytosine; 5-FU, 5-fluorouracil; GCV, ganciclovir; GvHD, graft-versus-host

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

ATR–Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity

Keywords: 5-FU، 5-fluorouracil; 5-FU, 5-fluorouracil; FUTP, fluorouridine triphosphate; FdUTP, fluorodeoxyuridine triphosphate; FdUMP, fluorodeoxyuridine monophosphate; TS, thymidylate synthase; BER, base excision repair; MMR, mismatch repair; DSB, double-strand break; HRR, homologous r

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2

Keywords: 5-FU، 5-fluorouracil; ICC, intrahepatic cholangiocarcinoma; ERK1/2, extracellular signal-regulated kinase 1/2; 5-FU, 5-fluorouracil; MEK, mitogen-activated protein kinase; PI3K, phosphoinocitide 3-kinaseCisplatin; Chemoresistance; Cholangiocarcinoma; AKT; ERK1/2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC–MS

Keywords: 5-FU، 5-fluorouracil; FBAL, α-fluoro-β-alanine; FUPA, α-fluoro-β-ureidopropionate; FUH2, 5-fluorodihydrouracil; 5-FU, 5-fluorouracil; 5-FdUrd, 5-fluoro-2′-deoxyuridineα-Fluoro-β-alanine (FBAL); α-Fluoro-β-ureidopropionate (FUPA); 5-Fluorodihydrouracil (FUH2); 5-Fluorouracil (5

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines

Keywords: 5-FU، 5-fluorouracil; Apoptosis; 1,4-Benzodioxin; 1,4-Benzoxathiin; eIF2α; Purine; Breast cancer cell line MCF-7; Neighboring-group participationMCF-7, Michigan Cancer Foundation; IC50, concentration resulting in 50% inhibition; 5-FU, 5-fluorouracil; SEM, standard error of the

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

R1 resection for aggressive or advanced colorectal liver metastases is justified in combination with effective prehepatectomy chemotherapy

Keywords: 5-FU، 5-fluorouracil; Colorectal cancer; Liver metastasis; Hepatectomy; R1 resection; SurvivalCA, Carbohydrate antigen; CDDP, Cisplatin; CEA, Carcinoembryonic antigen; CT, Computed tomography; DFR, Disease-free rate; FA, Folinic acid; 5-FU, 5-Fluorouracil; PD, Progressive dise

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه