A novel mechanism of XIAP degradation induced by timosaponin AIII in hepatocellular carcinoma
Keywords: اتوفاژی; Timosaponin AIII; Apoptosis; Autophagy; XIAP; Lysosomal proteolysis;
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Bovine lactoferricin B induces apoptosis of human gastric cancer cell line AGS by inhibition of autophagy at a late stage
Keywords: اتوفاژی; bovine lactoferricin B; gastric cancer; apoptosis; autophagy;
Autophagy is required for IL-2-mediated fibroblast growth
Keywords: اتوفاژی; IL-2; Autophagy; Apoptosis; Immunotherapy; HMGB1;
Autophagy contributes to ING4-induced glioma cell death
Keywords: اتوفاژی; ING4; Autophagy; Mitochondrial; Glioma cell;
ATM pathway is essential for ionizing radiation-induced autophagy
Keywords: اتوفاژی; ATM; Ionizing radiation; Autophagy;
PRIMA-1 induces autophagy in cancer cells carrying mutant or wild type p53
Keywords: اتوفاژی; PRIMA-1; Autophagy; p53; LC3; Electron microscopy;
Dietary Monascus adlay supplements facilitate suppression of cigarette smoke-induced pulmonary endoplasmic reticulum stress, autophagy, apoptosis and emphysema-related PLGF in the rat
Keywords: اتوفاژی; Acute lung injury; Apoptosis; Autophagy; Cigarette smoke; Endoplasmic reticulum stress; Oxidative stress;
The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots
Keywords: اتوفاژی; Autophagy; LC3-I/II; QDs; Synaptic plasticity; Synapsin-I; Synapse density; QD; quantum dot; LC3; light chain protein 3; PE; phosphatidylethanolamine; mTOR; mammalian target of rapamycin; LTP; long-term potentiation; I/O; input/output; PPF; paired-pulse f
Autophagy and mitophagy participate in ocular lens organelle degradation
Keywords: اتوفاژی; lens; differentiation; autophagy; mitophagy; cataract; electron microscopy; OFZ; organelle free zone; LC3B; microtubule-associated protein 1 light chain 3B; FYCO1; FYVE and coiled coil domain containing 1; TOM20; translocase of the outer mitochondrial mem
Phosphate-induced autophagy counteracts vascular calcification by reducing matrix vesicle release
Keywords: اتوفاژی; apoptosis; autophagy; chronic renal failure; hyperphosphatemia; oxidative stress;
Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease
Keywords: اتوفاژی; HD; Huntington's disease; htt; huntingtin; LC3; microtubule-associated protein light 3; mhtt; mutant huntingtin; NBR1; Neighbor of BRCA1 Gene 1; polyQ; polyglutamine; Nrf2; nuclear factor (erythroid-derived 2)-like 2; Xpo-1; exportin-1; Aggregates; Autoph
Involvement of endoplasmic reticulum and autophagy in microcystin-LR toxicity in Vero-E6 and HepG2 cell lines
Keywords: اتوفاژی; Microcystin-LR; Vero-E6 cells; HepG2 cells; Autophagy; Lysosomes; Endoplasmic reticulum;
RalGDS-dependent cardiomyocyte autophagy is required for load-induced ventricular hypertrophy
Keywords: اتوفاژی; Autophagy; Cardiac hypertrophy; Exocyst; Small GTPase;
bZIP transcription factor SmJLB1 regulates autophagy-related genes Smatg8 and Smatg4 and is required for fruiting-body development and vegetative growth in Sordaria macrospora
Keywords: اتوفاژی; Autophagy; bZIP transcription factor; Fruiting-body development; Sordaria macrospora;
Herp depletion protects from protein aggregation by up-regulating autophagy
Keywords: اتوفاژی; Poly-ubiquitinated protein; Endoplasmic reticulum stress; Autophagy; UPR; Protein aggregation; Beclin-1;
TRIM13 regulates caspase-8 ubiquitination, translocation to autophagosomes and activation during ER stress induced cell death
Keywords: اتوفاژی; Endoplasmic reticulum stress; Autophagy; Cell death; Ubiquitin ligase; TRIM13; Caspase-8;
Huang-Lian-Jie-Du-Decotion induced protective autophagy against the injury of cerebral ischemia/reperfusion via MAPK-mTOR signaling pathway
Keywords: اتوفاژی; HLJDD; Huang-Lian-Jie-Du-Decotion; MCAO; middle cerebral artery occlusion; TTC; 2,3,5-triphenyltetrazolium chloride; HE; hematoxylin-eosin; NO; nitric oxide; MDA; malondialdehyde; GSH; glutathione; GSSG; glutathione disulfide; T-SOD; total superoxide di
Molecular and cellular pharmacologyDual effect of capsaicin on cell death in human osteosarcoma G292 cells
Keywords: اتوفاژی; Capsaicin; Transient receptor potential vanilloid receptor; Autophagy; Osteosarcoma; Apoptosis;
Regulation of autophagosome formation by Rho kinase
Keywords: اتوفاژی; ROCK; Rho kinase; Autophagy; Autophagosome; Lysosome;
Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells
Keywords: اتوفاژی; Bortezomib; Apoptosis; Autophagy; Mitochondrial dysregulation; ER stress;
Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity
Keywords: اتوفاژی; Sirt1; Autophagy; PrP(106-126); Neurotoxicity; Mitochondrial dysfunction;
Balancing crosstalk between 20-hydroxyecdysone-induced autophagy and caspase activity in the fat body during Drosophila larval-prepupal transition
Keywords: اتوفاژی; Autophagy; Apoptosis; 20-Hydroxyecdysone; Fat body; Drosophila melanogaster;
Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1
Keywords: اتوفاژی; ERK; extracellular signal-regulated kinase; TSC-2; tuberous sclerosis 2 protein; mTOR; mammalian target of rapamycin; IRS; insulin receptor substrate; PI3K; phosphoinositide-3-kinase; AKT; protein kinase B; MAPK; mitogen-activated protein kinase; FOXO1; f
Carbamazepine suppresses calpain-mediated autophagy impairment after ischemia/reperfusion in mouse livers
Keywords: اتوفاژی; MPT; mitochondrial permeability transition; I/R; ischemia/reperfusion; CBZ; carbamazepine; FDA; Food & Drug Administration; Atg; autophagy-related proteins; KRH; Krebs-Ringer-N-2 hydroxyethylpiperazine-N-2 ethanesulfonic acid; PI; propidium iodide; TMRM
High glucose induces autophagy in podocytes
Keywords: اتوفاژی; Autophagy; High glucose; Podocytes; Oxidative stress;
Increased autophagy in peripheral nerves may protect Wistar Ottawa Karlsburg W rats against neuropathy
Keywords: اتوفاژی; Atg5; autophagy protein 5; Atg7; autophagy protein 7; CD3; cluster of differentiation 3; CD68/ED-1; cluster of differentiation 68; CMAP; compound muscle action potential; CNS; central nervous system; CY3; cyanine 3; D; dermis; E; epidermis; FITC; fluoresc
Evidence of intracellular stages in Trypanosoma (Megatrypanum) theileri in non-phagocytic mammalian cells
Keywords: اتوفاژی; Trypanosoma theileri; Intracellular stages; Autophagy; Lysosome; TGF-β;
Calyxin Y induces hydrogen peroxide-dependent autophagy and apoptosis via JNK activation in human non-small cell lung cancer NCI-H460 cells
Keywords: اتوفاژی; LC3; microtubule-associated protein1 light chain 3; JNK; c-Jun N-terminal protein kinases; ERK; extracellular signal-regulated kinases; MAPK; mitogen-activated protein kinase; Atgs; autophagy related genes; BCA; bicinchoninic acid; SDS-PAGE; sodium dode
Autophagy contributes to the survival of CD133+ liver cancer stem cells in the hypoxic and nutrient-deprived tumor microenvironment
Keywords: اتوفاژی; HCC; hepatocellular carcinoma; ATG; autophagy-related gene; LC3; microtubule-associated protein1 light chain 3; GFP-LC3; green fluorescent protein-linked LC3; CCK8; Cell Counting Kit-8; DAPI; 4â²,6â²-diamidino-2-phenylindole; PI; propidium iodide; FITC;
Ubiquitin receptors and protein quality control
Keywords: اتوفاژی; Ubiquitin; Proteasome; Ubiquilin; p62; Autophagy;
Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells
Keywords: اتوفاژی; Physalin A; A375-S2 cells; Apoptosis; Autophagy; p53; Noxa;
[Gly14]-Humanin reduces histopathology and improves functional outcome after traumatic brain injury in mice
Keywords: اتوفاژی; caspase-3; cysteinyl aspartate-specific protease-3; EDTA; ethylenediaminetetraacetic acid; HNG; [Gly14]-Humanin; LC3; microtubule-associated protein-1A/1B light chain 3; PARP; poly ADPribose-polymerase; PI; propidium iodide; SDS; sodium dodecyl sulfate; T
Suppression of Aβ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity
Keywords: اتوفاژی; Puromycin-sensitive aminopeptidase; Amyloid; Alzheimer; Autophagy; Proteolysis;
Crosstalk between apoptosis, necrosis and autophagy
Keywords: اتوفاژی; AIF; Apoptosis Inducing Factor; AMPK; Adenosine Monophosphate activated Kinase; APAF1; Apoptotic Protease Activating Factor 1; BCL-2; B-cell lymphoma 2; BCL-Xl; B-cell lymphoma extra large; BEC1; Beclin-1; BH; Bcl-2 homology; cIAP1; cellular inhibitor of
Initiation of autophagy and apoptosis by sonodynamic therapy in murine leukemia L1210 cells
Keywords: اتوفاژی; Sonodynamic therapy; Protoporphyrin IX; Apoptosis; Autophagy; L1210 cells;
Sorafenib enhances proteasome inhibitor-mediated cytotoxicity via inhibition of unfolded protein response and keratin phosphorylation
Keywords: اتوفاژی; Ab; antibody; ALLN; acetyl-leucyl-leucyl-norleucinal; ATF; activating transcription factor; CHOP; C/EBP homologous protein; DAPI; 4', 6-diamidino-2-phenylindole; eIF2; eukaryotic translation-initiation factor 2; ER; endoplasmic reticulum; GADD153; growth
N-terminally truncated forms of human cathepsin F accumulate in aggresome-like inclusions
Keywords: اتوفاژی; Î19CatF; truncated form of human cathepsin F (Ala20-Asp484); Î125CatF; truncated form of human cathepsin F (Pro126-Asp484); Î146CatF; truncated form of human cathepsin F (Met147-Asp484); HRP; horseradish peroxidase; Mw; molecular weight; wtCatF;
Activation of autophagy by globular adiponectin attenuates ethanol-induced apoptosis in HepG2 cells: Involvement of AMPK/FoxO3A axis
Keywords: اتوفاژی; Adiponectin; AMPK; Apoptosis; Autophagy; Ethanol; FoxO3;
Identification of a small molecule that induces ATG5-and-cathepsin-l-dependent cell death and modulates polyglutamine toxicity
Keywords: اتوفاژی; APH; aphidicolin; ATG; Autophagy gene; DKO; double knockout; 3-MA; 3-methyl adenine; HU; Hydroxyurea; MEF; mouse embryo fibroblasts; NID; Novel inducer of death; PI3K; phosphotidyl inositol 3-kinase; RIP-1; Receptor Interacting Protein-1, STS, staurospori
The modality of cell-particle interactions drives the toxicity of nanosized CuO and TiO2 in human alveolar epithelial cells
Keywords: اتوفاژی; A549; Nanoparticles; Copper oxide; Titanium dioxide; Autophagy; Microscopy;
Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation
Keywords: اتوفاژی; Autophagy; ROS; Mitochondria; AMPK;
Autophagy, polyphenols and healthy ageing
Keywords: اتوفاژی; AD; Alzheimer's disease; AMP; adenosine monophosphate; AMPK; adenosine monophosphate activated protein kinase; APP; amyloid beta precursor protein; Atg; autophagy (related gene); ATP; adenosine triphosphate; AV; autophagic vacuoles; Aβ; amyloid beta; Bcl
PP2A blockade inhibits autophagy and causes intraneuronal accumulation of ubiquitinated proteins
Keywords: اتوفاژی; Autophagy; Neuron; PP2A; Protein aggregation; Alzheimer's disease;
Propofol prevents cerebral ischemia-triggered autophagy activation and cell death in the rat hippocampus through the NF-κB/p53 signaling pathway
Keywords: اتوفاژی; 3-MA; 3-methyladenine; ANOVA; analysis of variance; BSA; bovine serum albumin; DMSO; dimethylsulfoxide; DRAM; damage-regulated autophagy modulator; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; H/I; hypoxia-ischemia; I/R; ischemia-reperfusion; PaCO
mTOR-independent autophagy counteracts apoptosis in herpes simplex virus type 1-infected U251 glioma cells
Keywords: اتوفاژی; HSV-1; Autophagy; Apoptosis; mTOR; AMP-activated protein kinase; Akt;
Autophagy in obesity and atherosclerosis: Interrelationships between cholesterol homeostasis, lipoprotein metabolism and autophagy in macrophages and other systems
Keywords: اتوفاژی; Autophagy; Lipid metabolism; Atherosclerosis; Macrophage; Lipoprotein;
The role of autophagy in doxorubicin-induced cardiotoxicity
Keywords: اتوفاژی; Doxorubicin; Autophagy; Cardiotoxicity; Adriamycin
Beclin-1: Autophagic regulator and therapeutic target in cancer
Keywords: اتوفاژی; Beclin-1; Autophagy; Interactome; Cancer
Autophagy Therapeutic Potential of Garlic in Human Cancer Therapy
Keywords: اتوفاژی; Autophagy; Cancer; Complementary therapy; Garlic
Turning a frown upside down: Exploiting nanoparticle toxicity for anticancer therapy
Keywords: اتوفاژی; Nanoparticles; Nanotoxicology; Cancer therapy; Autophagy; Particle degradation; Quantum dot; Zinc oxide