دانلود مقالات ISI درباره P53 + ترجمه فارسی

Arsenic-induced S phase cell cycle lengthening is associated with ROS generation, p53 signaling and CDC25A expression

Keywords: Arsenite; p53; S phase lengthening; ROS; SESN1; CDC25A;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

All-trans retinoic acid induces p53-depenent apoptosis in human hepatocytes by activating p14 expression via promoter hypomethylation

Keywords: All-trans retinoic acid; Apoptosis; DNA methylation; p53; p14

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Nutraceutical activators of AMPK/Sirt1 axis inhibit viral production and protect neurons from neurodegenerative events triggered during HSV-1 infection

Keywords: HSV-1; AMPK; Sirt1; p53; Resveratrol; Quercetin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Protosappanin B protects PC12 cells against oxygen–glucose deprivation-induced neuronal death by maintaining mitochondrial homeostasis via induction of ubiquitin-dependent p53 protein degradation

Keywords: Protosappanin B (PubChem CID: 102036-29-3)Mitochondrial dysfunction; p53; Ubiquition-dependent degradation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Tanshinone IIA inhibits viral oncogene expression leading to apoptosis and inhibition of cervical cancer

Keywords: Cervical cancer; Tanshinone IIA; HPV E6/E7 oncogenes; Tumor suppressor genes; Apoptosis; p53;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Sesquiterpene lactones of Moquiniastrum polymorphum subsp. floccosum have antineoplastic effects in Walker-256 tumor-bearing rats

Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; Cat; catalase; DNCB; 2,4-dinitrochlorobenzene; EDTA; ethylenediaminetetraacetic acid; EtOAc; ethyl acetate; F1B; dichloromethane fra

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Pyruvate kinase isoenzyme M2 is a therapeutic target of gemcitabine-resistant pancreatic cancer cells

Keywords: Gem; gemictabine; PKM2; pyruvate kinase isoenzymes muscle type 2; CASP3/7; caspase 3 & 7; c. PARP; cleaved poly ADP ribose polymerase; BAX; BCL2-associated X protein; CDKN1A; cyclin-dependent kinase inhibitor 1A; BAK1; BCL2-antagonist; Bcl-xL; BCL2-like 1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival

Keywords: FAK; p53; SH-EP; WAC(2); Neuroblastoma

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Overexpression of CRM1: A Characteristic Feature in a Transformed Phenotype of Lung Carcinogenesis and a Molecular Target for Lung Cancer Adjuvant Therapy

Keywords: Lung cancer; CRM1; p53; Leptomycin B; Combination therapy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury

Keywords: Traumatic brain injury (TBI); p53; Pifithrin-α (PFT-α); PFT-α oxygen analog; Apoptosis; Controlled cortical impact

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Involvement of dysregulated Wip1 in manganese-induced p53 signaling and neuronal apoptosis

Keywords: GFAP, glial fibrillary acidic protein; Wip1, wild-type p53-induced phosphatase 1; IPD, idiopathic Parkinson’s disease; NGF, nerve growth factor; Mn, manganeseManganese; Wip1; p53; Neurotoxicity; Apoptosis; Striatum

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

microRNA-107 functions as a candidate tumor suppressor gene in renal clear cell carcinoma involving multiple genes

Keywords: Renal cell carcinoma; EIF5; p53; VHL; MicroRNA; miR-107;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Suppression of centrosome protein TACC3 induces G1 arrest and cell death through activation of p38–p53–p21 stress signaling pathway

Keywords: Centrosome; Cell cycle; TACC3; p53; p38; p21

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Actinomycin D and nutlin-3a synergistically promote phosphorylation of p53 on serine 46 in cancer cell lines of different origin

Keywords: p53; MDM2; Nucleolar stress; Serine 46; Apoptosis; Autophagy;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The regulation of radiosensitivity by p53 and its acetylation

Keywords: P53; Acetylation; Radiotherapy; Radio sensitivity; Posttranslational modifications

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Human DMTF1β antagonizes DMTF1α regulation of the p14ARF tumor suppressor and promotes cellular proliferation

Keywords: Human DMP1; Human DMTF1; p14ARF; ARF; p53; Leukemia;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Upregulation of miR-34a-5p antagonizes AFB1-induced genotoxicity in F344 rat liver

Keywords: Aflatoxin B1; miR-34a-5p; P53; DNA damage; Genotoxicity

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis

Keywords: Diabetic retinopathy; Glucagon-like peptide-1 receptor; Reactive oxygen species; Endoplasmic reticulum stress; P53;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Alphitolic acid, an anti-inflammatory triterpene, induces apoptosis and autophagy in oral squamous cell carcinoma cells, in part, through a p53-dependent pathway

Keywords: Alphitolic acid; Oral squamous cell carcinoma; Apoptosis; Autophagy; p53;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

RETRA exerts anticancer activity in Ewing's sarcoma cells independent of their TP53 status

Keywords: Cancer therapy; Ewing's sarcoma; RETRA; p53; p73; Apoptosis; Cell cycle; Gene expression;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

A tumor-targeting p53 nanodelivery system limits chemoresistance to temozolomide prolonging survival in a mouse model of glioblastoma multiforme

Keywords: p53; Chemosensitization; Systemic nanodelivery; Temozolomide; Glioblastoma multiforme; Limiting TMZ-resistance;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Co-delivery of doxorubicin and tumor-suppressing p53 gene using a POSS-based star-shaped polymer for cancer therapy

Keywords: POSS; Amphiphilic micelles; Doxorubicin; P53; Co-delivery; Cancer therapy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism

Keywords: p53; p44; AICD; IRES; Aging; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing

Keywords: AD; adefovir dipivoxil; AhR; aryl hydrocarbon receptor; AMIO; amiodarone; APAP; acetaminophen; ATF4; activating transcription factor 4; CAA; chloroacetaldehyde; CdCl2; cadmium chloride; ChIP-seq; chromatin immunoprecipitation followed by DNA sequencing; C

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells

Keywords: ABC transporter; Myriocin; p53; Proliferation; RNA interference; Sphingolipids;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Novel structurally similar chromene derivatives with opposing effects on p53 and apoptosis mechanisms in colorectal HCT116 cancer cells

Keywords: HCT116 cancer cells; Cytotoxicity; P53; Apoptosis; Chromene derivatives

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo

Keywords: p53; pRB; Resistance; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Ectopic AP4 expression induces cellular senescence via activation of p53 in long-term confluent retinal pigment epithelial cells

Keywords: AP4; p53; Cellular senescence; Serum activation

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Pifithrin-α ameliorates resveratrol-induced two-cell block in mouse preimplantation embryos in vitro

Keywords: Resveratrol; Two-cell block; Apoptosis; p53; Pifithrin-α; Preimplantation embryo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

X-ray and ultraviolet C irradiation-induced γ-H2AX and p53 formation in normal human periosteal cells in vitro: markers for quality control in cell therapy

Keywords: cell cycle; γ-H2AX; oxidative stress; p53; periosteal cells; quality control;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Dynamin-related protein 1 mediates mitochondria-dependent apoptosis in chlorpyrifos-treated SH-SY5Y cells

Keywords: Chlorpyrifos; Dynamin-related protein 1; p53; Mitochondrial-division inhibitor-1; Reactive oxidative species; Mitogen-activated protein kinase

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Depletion of poly(A)-specific ribonuclease (PARN) inhibits proliferation of human gastric cancer cells by blocking cell cycle progression

Keywords: BSA; bovine serum albumin; CDK; cyclin-dependent kinase; DDR; DNA damage response; DMEM; Dulbecco's modified Eagle's medium; EEP; endonuclease-exonuclease-phosphatase; HRP; Horseradish peroxidase; HU; hydroxyl urea; M-MLV; Moloney murine leukemia viru

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Interaction of p53 with prolyl isomerases: Healthy and unhealthy relationships

Keywords: Peptidyl-prolyl cis/trans isomerases; Pin1; p53; Apoptosis; Neurodegenerative diseases; Cancer;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1 contributes to aldose reductase expression through modulating NFAT5 under osmotic stress: In vitro and in silico insights

Keywords: AK; acetyllysine; AP-1; activator protein 1; AR; aldose reductase; BGT1; betaine/gamma-aminobutyric acid transporter; Egr-1; early growth response protein 1; FSP27; fat-specific protein 27; HSP90; heat shock protein 90; NAD+; nicotinamide adenine dinucleo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

5-Lipoxygenase is a direct p53 target gene in humans

Keywords: ALOX5; arachidonate 5-lipoxygenase gene; 5-LO; 5-lipoxygenase; PTMs; posttranslational modifications; AA; arachidonic acid; 5-HETE; 5-hydroxyeicosatetraenoic acid; LT; leukotriene; FLAP; 5-lipoxygenase activating protein; HEPES; 4-(2-hydroxyethyl)-1-piper

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Hyperglycemia, p53, and mitochondrial pathway of apoptosis are involved in the susceptibility of diabetic models to ischemic acute kidney injury

Keywords: acute kidney injury; diabetic nephropathy; high glucose; ischemia-reperfusion; mitochondria; p53;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Structural and sequential context of p53: A review of experimental and theoretical evidence

Keywords: p53; Mutation; Thermodynamic; Molecular dynamics simulation; Small molecule inhibitor;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Cadmium treatment suppresses DNA polymerase δ catalytic subunit gene expression by acting on the p53 and Sp1 regulatory axis

Keywords: AP; abasic site; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; Cd; cadmium; CNS; central nervous system; DNA LigI; DNA ligase I; MMS; methyl methanesulfonate; OGG1; 8-oxoguanine DNA glycosylase; Polβ; DNA polymerase β; Polδ; po

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells

Keywords: Chaetoglobosin K; Ovarian cancer; Apoptosis; Cell cycle arrest; p53; p38;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

PEGylated-thymoquinone-nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a

Keywords: Thymoquinone; Cell migration; p53; miR-34a; Rac1; Actin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Cardamonin induces autophagy and an antiproliferative effect through JNK activation in human colorectal carcinoma HCT116 cells

Keywords: Cardamonin; Autophagy; Antiproliferation; Colorectal carcinoma; p53; c-Jun N-terminal kinase (JNK);

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Schistosoma haematobium egg-induced bladder urothelial abnormalities dependent on p53 are modulated by host sex

Keywords: Bladder cancer; Schistosomiasis; Schistosoma; Schistosoma haematobium; Haematobium; Bilharzia; p53; Ulceration; Urothelium; Urothelial;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuin 7 promotes cellular survival following genomic stress by attenuation of DNA damage, SAPK activation and p53 response

Keywords: TUNEL; Terminal deoxynucleotidyl transferase dUTP nick end labelling; EdU; 5-ethynyl-2′-deoxyuridine; PI; Propidium iodide; DAPI; 4′,6-diamidino-2-phenylindole; HR; Homologous recombination; NHEJ; Non homologous end joining; SA-β-gal; Senescence asso

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Antioxidant activity and anti-proliferative effect of a bioactive peptide from chickpea (Cicer arietinum L.)

Keywords: Synthetic peptide; p53; Antioxidant activity; Antiproliferative effect; Molecular docking;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

P53-dependent miRNAs mediate nitric oxide-induced apoptosis in colonic carcinogenesis

Keywords: Nitric oxide; Apoptosis; Inflammation; Colon cancer; miRNA; p53;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2015 سفارش ترجمه

Estimation of TiO2 nanoparticle-induced genotoxicity persistence and possible chronic gastritis-induction in mice

Keywords: TiO2 nanoparticles; Chronic gastritis; Genotoxicity; p53; Mice;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and cytotoxic activity of MOM-ether analogs of isosteviol

Keywords: XOGHKSPSZUMWSW-DLVPKPCGSA-N; MBEXDVODIOJSHS-OVWDBLRBSA-N; SHKJSFWJVKXKMC-WTTUNBIBSA-N; JXBMAQPSDYYPJG-LHAFMROOSA-N; DGGPEEYHUQAZIT-SIQVWGOZSA-N; ZCMULAIBYWUMFO-LFJMRGCMSA-N; IOMQVFBKFJIBDB-SIQVWGOZSA-N; DMXYKZDFNHUYNQ-WTTUNBIBSA-N; YADQWCRDIBHUGG-SMMOOYLE

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

The impact of R213 mutation on p53-mediated p21 activity

Keywords: p53; Mutation; Arginine; p21; WAF1; wild-type p53-activated fragment 1; MDM2; mouse double minute 2 homolog; GADD45; the growth arrest and DNA damage-inducible 45; Bax; Bcl-2-associated X protein; PRMT5; protein arginine methyltransferase 5; DMEM; Dulbecc

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

An autophagic switch in the response of tumor cells to radiation and chemotherapy

Keywords: Autophagy; Cytoprotective; Cytotoxic; Nonprotective; Cytostatic; p53;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Study of the biologic behavior of odontogenic keratocyst and orthokeratinaized odontogenic cyst using TGF-alpha and P53 markers

Keywords: Odontogenic keratocyst; Orthokeratinized odontogenic cyst; P53; TGF-alpha

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه