
Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: Underlying mechanisms
Keywords: پروستاگلاندین ها; sickness behavior; cytokines; prostaglandins; interferons; neurodegenerative disease; microgliaAD, Alzheimer's disease; BBB, blood–brain barrier; COX, cyclooxygenase; CRF, corticotrophin-releasing; EAE, experimental acute encephalitis; EP1, prostaglandin