S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer
Keywords: Colon cancer; S100P; RAGE; miR-155; AP-1; miR-155 sponge;
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Rokumi-jio-gan-containing prescriptions regulate oxidative stress through improving dyslipidemia in a subtotal nephrectomized rat model
Keywords: AGE; advanced glycation endproduct; Cr; creatinine; Ccr; creatinine clearance; COX-2; cyclooxygenase-2; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; GSH; reduced glutathione; GSSG; oxidized
Protection of glycyrrhizic acid against AGEs-induced endothelial dysfunction through inhibiting RAGE/NF-κB pathway activation in human umbilical vein endothelial cells
Keywords: AGEs advanced; glycation end products; ROS; reactive oxygen species; GA; glycyrrhizic acid; HUVECs; human umbilical vein endothelial cells; AO/EB; acridine orange/ethidium bromide; BSA; non-glycated bovine serum albumin; AG; aminoguanidine; VE; Vitamin E;
The protection of 4,4â²-diphenylmethane-bis(methyl) carbamate from Cortex Mori on advanced glycation end product-induced endothelial dysfunction: Via inhibiting AGE formation or blocking AGEs-RAGE axis?
Keywords: 4,4â²-diphenylmethane-bis(methyl) carbamate; AGE formation; RAGE; Fluorescence quenching; Fluorescence polarization; Diabetic vascular complications;
Beneficial effects of quinoline-3-carboxamide (ABR-215757) on atherosclerotic plaque morphology in S100A12 transgenic ApoE null mice
Keywords: Atherosclerosis; S100 proteins; RAGE; Quinoline-3-carboxamides;
Blockage of CR1 prevents activation of rodent microglia
Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; Apo; apocynin; APP; amyloid precursor protein; CGC; cerebellar granule cells; CR1; complement receptor 1; DIV; days in vitro; DHE; dihydroethidium; D-MEM; Dulbecco's modified eagle medium; EA; ethacrynic acid; E
Cellular signalling of the receptor for advanced glycation end products (RAGE)
Keywords: RAGE; Advanced glycation end-product; HMGB1; S100; Inflammation; NFκB;
CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction
Keywords: Act1; activator of NF-κB; AOPPs; advanced oxidation protein products; AGE; advanced glycation end product; AP-1; activator protein-1; C/EBP; CCAAT/enhancer-binding protein; CIKS; connection to IKK and SAPK/JNK; DCFH-DA; 2â²,7â²-dichlorofluorescin-diace
Vitamin A (retinol) downregulates the receptor for advanced glycation endproducts (RAGE) by oxidant-dependent activation of p38 MAPK and NF-kB in human lung cancer A549 cells
Keywords: Retinol; RAGE; Lung; Oxidative stress; p38/MAPK, NF-kB;
Differential expression of monocyte surface markers among TB patients with diabetes co-morbidity
Keywords: Tuberculosis; Diabetes; Monocyte; Innate immunity; CCR2; CD11b; RAGE
L-165,041, troglitazone and their combination treatment to attenuate high glucose-induced receptor for advanced glycation end products (RAGE) expression
Keywords: PPAR gamma; PPAR delta; Diabetic nephropathy; RAGE; Apoptosis
A study on serum advanced glycation end products and its association with oxidative stress and paraoxonase activity in type 2 diabetic patients with vascular complications
Keywords: T2DM, type 2 diabetes mellitus; AGEs, advanced glycation end products; PON1, paraoxonase; OS, oxidative stress; PCO, protein carbonyl; AOPP, advanced oxidation protein products; MDA, malonyldialdehyde; T-SH, total thiol; ROS, reactive oxygen species; RAGE
HMGB1 and leukocyte migration during trauma and sterile inflammation
Keywords: CXCL12; CXCR4; Chemokine; RAGE; TLR4; Oxidation
Exendin-4 and GLP-1 decreases induced expression of ICAM-1, VCAM-1 and RAGE in human retinal pigment epithelial cells
Keywords: RAGE; incretins; human retinal pigment epithelium; adhesion molecules; AGE
Morpho-mechanical intestinal remodeling in type 2 diabetic GK rats—Is it related to advanced glycation end product formation?
Keywords: Type 2 diabetes; GK rats; Jejunum; Histomorphometry; Biomechanics; AGE; RAGE; Remodeling
The immunobiology of the receptor of advanced glycation end-products: Trends and challenges
Keywords: Alarmins; DAMPs; Innate immunity; Inflammation; RAGE; PAMPs; Toll receptors
Cloning and characterization of new transcript variants of insulin-like growth factor-I in Sika deer (Cervus elaphus)
Keywords: Sika deer; IGF-I; Transcript variants; RAGE; Semi-quantitative RT-PCR;
Schistosoma mansoni infection causes oxidative stress and alters receptor for advanced glycation endproduct (RAGE) and tau levels in multiple organs in mice
Keywords: Schistosoma; Oxidative stress; RAGE; Tau; Antioxidant enzymes
Short CommunicationLocal and systemic occurrences of HMGB1 in gnotobiotic piglets infected with E. coli O55 are related to bacterial translocation and inflammatory cytokines
Keywords: HMGB1; Enteric infection; E. coli; Cytokine; Gnotobiotic piglet; HMGB1; high mobility group box protein 1; RAGE; receptor for advanced glycation end products; TNF-α; tumor necrosis factor alpha;
Analysis of AGE modified proteins and RAGE expression in HER2/neu negative invasive ductal carcinoma
Keywords: Breast cancer; Advanced glycation end products; RAGE;
Association between sRAGE, esRAGE levels and vascular inflammation: Analysis with 18F-fluorodeoxyglucose positron emission tomography
Keywords: Atherosclerosis; Inflammation; RAGE; Positron emission tomography; Type 2 diabetes
Receptor for advanced glycation end products inhibits proliferation in osteoblast through suppression of Wnt, PI3K and ERK signaling
Keywords: RAGE; Cell proliferation; PI3K; Wnt; ERK;
Ischemia-induced hyperglycemia: Consequences, neuroendocrine regulation, and a role for RAGE
Keywords: RAGE; Hyperglycemia; Ischemia; Corticosterone; Insulin
Association analysis of â429T/C and â374T/A polymorphisms of receptor of advanced glycation end products (RAGE) gene in Malaysian with type 2 diabetic retinopathy
Keywords: Diabetic retinopathy; Polymorphism; RAGE;
Pravastatin inhibits advanced glycation end products (AGEs)-induced proximal tubular cell apoptosis and injury by reducing receptor for AGEs (RAGE) level
Keywords: AGEs; advanced glycation end products; RAGE; receptor for AGEs; CKD; chronic kidney disease; ROS; reactive oxygen species; BSA; bovine serum albumin; GGPP; geranylgeranyl pyrophosphate; Ab; antibody; ADMA; asymmetric dimethylarginine; RAGE-Ab; Ab raised a
Targeting receptor for advanced glycation end products (RAGE) expression induces apoptosis and inhibits prostate tumor growth
Keywords: RAGE; HMGB1; RNAi; Apoptosis and prostate cancer
Receptor for advanced glycation end products (RAGE) and glyoxalase I gene polymorphisms in pathological pregnancy
Keywords: Receptor for advanced glycation end products; RAGE; Soluble RAGE; sRAGE; Glyoxalase I; Polymorphism; Preterm labor; Preeclampsia; Pregnancy intrahepatic cholestasis; Intrauterine growth restriction;
Peripheral RAGE (Receptor for Advanced Glycation Endproducts)-ligands in normal pregnancy and preeclampsia: novel markers of inflammatory response
Keywords: AGEs; RAGE; HMGB1; S100A12; Preeclampsia; Pregnancy
Tissue plasminogen activator treatment of stroke in type-1 diabetes rats
Keywords: AGE; advanced glycation end-product; BBB; blood-brain barrier; DM; diabetes mellitus; ECA; external carotid artery; H&E; hematoxylin and eosin; HMGB1; high-mobility group box 1; IBZ; ischemic border area; ICA; internal carotid artery; MCAo; middle cereb
Association study of polymorphisms in the receptor for advanced glycation end-products (RAGE) gene with susceptibility and prognosis of heart failure
Keywords: ACE; angiotensin converting enzyme; AGEs; advanced glycation end-products; CI; confidence interval; cRAGE; cleaved RAGE; esRAGE; endogenously secreted RAGE; HF; heart failure; HWE; Hardy-Weinberg equilibrium; OR; odds ratio; RAGE; receptor for advanced
Advanced glycation endproducts in horses with insulin-induced laminitis
Keywords: AGE, advanced glycation endproduct; ECM, extracellular matrix; GLUT, facilitative glucose transporter; MDA, malondialdehyde; RAGE, receptor for advanced glycation endproduct; ROS, reactive oxygen speciesEquine; Glucose; AGE; RAGE; GLUT-1; Oxidative stress
Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells
Keywords: AD; Alzheimer's disease; Aβ; amyloid beta; ART; antiretroviral therapy; BBB; blood-brain barrier; cav-1; caveolin-1; FTS; farnesylthiosalicylic acid; HAND; HIV-associated neurocognitive disorders; HBMEC; human brain microvascular endothelial cells; HEK
The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes
Keywords: Glycation; Diabetes; Complications; RAGE
Combining the observation of cell morphology with the evaluation of key inflammatory mediators to assess the anti-inflammatory effects of geranyl flavonoid derivatives in breadfruit
Keywords: AC-1; 6-geranyl-7,4â²-dihydroxyflavanone; AC-2; 4,2â²,4â²-trihydroxy-3â²-[6-hydroxy-3,7-dimethyl-2(E),7-octadienyl]chalcone; AC-3; 3,4,2â²,4â²-tetrahydroxy-3â²-geranyldihydrochalcone; AC-4; 4,2â²,4â²-trihydroxy-5â²-geranyldihydrochalcone; THP-1;
Involvement of HMGB1 and RAGE in IL-1β-induced gingival inflammation
Keywords: IL-1β; Gingiva; HMGB1; RAGE;
High circulating levels of S100A8/A9 complex (calprotectin) in male Japanese with abdominal adiposity and dysregulated expression of S100A8 and S100A9 in adipose tissues of obese mice
Keywords: MAF; mature adipocytes fraction; RAGE; receptor for advanced glycation end-products; SAA3; serum amyloid A 3; SVF; stromal vascular cell fraction; TLR4; toll-like receptor 4; S100A8; S100A9; Calprotectin; Adiposity;
Anti-Aβ-MAb and dually decorated nanoliposomes: Effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells
Keywords: Targeting; Amyloid; Abeta peptides; RAGE; Blood–brain barrier; Transcytosis
Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes
Keywords: AGE; Oxidative stress; RAGE; Diabetic vascular complication;
A meta-analysis of receptor for advanced glycation end products gene: Four well-evaluated polymorphisms with diabetes mellitus
Keywords: RAGE; Diabetes mellitus; Polymorphism; Association; Meta-analysis
ER stress is associated with reduced ABCA-1 protein levels in macrophages treated with advanced glycated albumin - Reversal by a chemical chaperone
Keywords: ABCA-1; ATP binding cassette transporter class A type I; ABCG-1; ATPbinding cassette transporter class G type I; AGE; advanced glycation end products; AGE-alb; advanced glycated albumin; Apo A-I; apolipoprotein A-I; ATF6; activating transcription factor 6
Research ArticleEndogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis
Keywords: NAFLD; nonalcoholic fatty liver disease; CML; Nε-(carboxymethyl)lysine; RAGE; receptor for advanced glycation endproducts; UPLC; ultra performance liquid chromatography; MS; mass spectrometry; ALAT; alanine aminotransferase; ASAT; aspartate aminotransfer
RAGE signaling mediates post-injury arterial neointima formation by suppression of liver kinase B1 and AMPK activity
Keywords: RAGE; AMPK; LKB1; Arterial restenosis; Neointimal hyperplasia;
Role of advanced glycation end products in hypertension and cardiovascular risk: human studies
Keywords: Advanced glycation end-products (AGEs); RAGE; N-epsilon-(carboxymethyl)lysine (CML); blood pressure; large artery stiffness; microcirculation
HMGB1 in vascular diseases: Its role in vascular inflammation and atherosclerosis
Keywords: HMGB1; RAGE; TLRs; Vasculitis; Atherosclerosis
Immunohistochemical localization of receptor for advanced glycation end (RAGE) products in the R6/2 mouse model of Huntington's disease
Keywords: RAGE; R6/2; Immunohistochemistry; Huntington's disease; Confocal microscopy
S100B-RAGE dependent VEGF secretion by cardiac myocytes induces myofibroblast proliferation
Keywords: VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth receptor; LUX; luciferase; αSMA; α smooth muscle actin; SMMHC; smooth muscle myosin heavy chain; RAGE; receptor for advanced glycation end products; MAPK; mitogen activated kin
Prostaglandin E2 stimulates S100A8 expression by activating protein kinase A and CCAAT/enhancer-binding-protein-beta in prostate cancer cells
Keywords: BSA; bovine serum albumin; cAMP; cyclic AMP; ChIP; chromatin immunoprecipitation; C/EBPβ; CCAAT/enhancer-binding-protein-beta; CM; conditioned medium; COX-2; cyclooxygenase-2; CREB; cAMP response element binding protein; EP; prostaglandin E receptor; ERK
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
Keywords: AP-1; activator protein-1; ASC; apoptosis-associated speck-like protein containing a CARD domain; ASK; apoptosis signal-regulating kinase; ATM; Ataxia Telangiectasia Mutated; ATR; ATM and Rad 3-related; BRCA1; breast cancer 1; CARD; caspase activation and
Aminoguanidine normalizes ET-1-induced aortic contraction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats by suppressing Jab1-mediated increase in ETA-receptor expression
Keywords: AG; aminoguanidine; AGEs; advanced glycation end-products; CML; N epsilon-(carboxymethyl) lysine; ECE1; endothelin converting enzyme; ERK; extracellular signal-regulated kinase; ET-1; endothelin-1; ETA-R; endothelin type A receptor; ETB-R; endothelin type
Rage Attacks in Pediatric Obsessive-Compulsive Disorder: Phenomenology and Clinical Correlates
Keywords: obsessive-compulsive disorder; rage; anger attacks; treatment;