Is inflammatory bowel disease in dogs and cats associated with a Th1 or Th2 polarization?
Keywords: Canine; Chronic enteropathy; Inflammatory bowel disease; Th1; Th2; Th17;
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Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques
Keywords: ApoEâ/â;  apolipoprotein E knockout; HO-1; heme oxygenase-1; IL-4; interleukin 4; IL-10; interleukin 10; IL-12; interleukin 12; IL-13; interleukin 13; IFN-γ; interferon gamma; iNOS; inducible nitric oxide synthase; IRF5; interferon regulatory factor
Elevated Semaphorin 5A correlated with Th1 polarization in patients with chronic immune thrombocytopenia
Keywords: Immune thrombocytopenia; Semaphorin 5A; Th1; Cytokines; Treatment;
BALB/c mice display more enhanced BCG vaccine induced Th1 and Th17 response than C57BL/6 mice but have equivalent protection
Keywords: Tuberculosis; BCG; Vaccine; Th1; Th17;
Visualization of the human CD4+ T-cell response in humanized HLA-DR4-expressing NOD/Shi-scid/γcnull (NOG) mice by retrogenic expression of the human TCR gene
Keywords: TCR; Humanized mice; NOG mice; HLA-DR4; Th1;
Escherichia coli maltose-binding protein (MBP) directly induces mouse Th1 activation through upregulating TLR2 and downregulating TLR4 expressions
Keywords: Maltose-binding protein, MBP; CD4+ T cell; Th1; TLR2; TLR4
The transcriptional programs of iNKT cells
Keywords: α-GalCer; α-galactosylceramide; BTB-POZ-ZF; broad complex, tramtrack, bric-a-brac or poxvirus and zinc finger; CCR2; C-C chemokine receptor type 2; CCR10; C-C chemokine receptor type 10; ChIP-seq; chromatin immunoprecipitation with deep sequencing
L’interleukine-33 : une cible thérapeutique potentielle de la néo-angiogenèse associée à l’asthme
Keywords: IL-33; ST2; Asthme; Endothélium; Épithélium; Th2; Th1IL-33; ST2; Asthma; Endothelium; Epithelium; Th2; Th1
Mucosal vaccination by the intranasal route. Nose-associated lymphoid tissue (NALT)-Structure, function and species differences
Keywords: BrdU; Bromodesoxy Uridine; CV; conventional; DC; dendritic cell; GF; germ free; HEV; high endothelial venule; MAdCAM-I; mucosal adhesion molecule; MALT; mucosa-associated lymphoid tissue; M cell; microfold cell; NALT; nose-associated lymphoid tissue; PNAd
Alteration of circulating type 2 follicular helper T cells and regulatory B cells underlies the comorbid association of allergic rhinitis with bronchial asthma
Keywords: AR; allergic rhinitis; Tfh; follicular helper T; Breg; regulatory B; Ig; immunoglobulin; Th1; type 1 helper CD4+ T; Th2; type 2 helper CD4+ T; TSLP; thymic stromal lymphopoietin; IL; interleukin; Tfh1; type 1 Tfh; Tfh2; type 2 Tfh; Tfh17; IL-17-producing
Gut microbiota biomodulators, when the stork comes by the scalpel
Keywords: B; Bifidobacterium; CS; Caesarean section; C; Clostridium; CAMPs; commensal associated molecular patterns; DCs; dendritic cells; EPS; exopolysaccharide; ESPACI; European Society for Paediatric Allergology and Clinical Immunology; ESPGHAN; European Society
Tetravalent dengue DIIIC protein together with alum and ODN elicits a Th1 response and neutralizing antibodies in mice
Keywords: DIII; E domain III; C; capsid; DENV; dengue virus; Tetra DIIIC; combination of fusion proteins of E domain III protein (DIII) and the capsid (C) protein of each DENV serotype; Dengue; Vaccine; Recombinant protein; T cell response; Th1; Antibodies; Alum; O
CD226 as a genetic adjuvant to enhance immune efficacy induced by Ag85A DNA vaccination
Keywords: Ag85A; antigen-85A; Th1; type 1 helper T lymphocytes; MLNs; mesenteric lymph nodes; BCG; Bacillus Calmette-Guerin; DCs; dendritic cells; DNAM-1; DANX accessory molecule-1; HEK293; human embryo kidney 293; LPLs; lamina propria lymphocytes; T-LPLs; T cells
Evaluation of in situ expression of effector and regulatory cytokines, TLR, galectins and matrix metalloproteinases in oral manifestations of paracoccidioidomycosis
Keywords: FoxP3; forkhead box P3; Gal-1; galectin 1; Gal-3; galectin 3; Gal-9; galectin 9; IL-4; interleukin-4; IL-10; interleukin-10; IL-17; interleukin-17; IFN-γ; interferon-gamma; GM-CSF; granulocytemacrophage colony-stimulating factor; MMPs; matrix metalloprot
BRIEF COMMUNICATIONTransforming growth factor-β1 regulated phosphorylated AKT and interferon gamma expressions are associated with epithelial cell survival in rhesus macaque colon explants
Keywords: AC-3; active caspase-3; EC; epithelial cells; MAb; monoclonal antibody; pAKT; phosphorylated AKT; RM; rhesus macaque; TGF-β; transforming growth factor-beta; rTGF-β; recombinant TGF-β; Th1; T-helper 1; Apoptosis; Colon; Epithelial cell; pAKT; Rhesus ma
Atopic dermatitis and skin diseaseAlopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing
Keywords: Alopecia areata; TÂ cell; TH1; TH2; IL-23; hair keratin; atopic dermatitis; AA; Alopecia areata; AD; Atopic dermatitis; AT; Alopecia totalis; AU; Alopecia universalis; DC; Dendritic cell; DEG; Differentially expressed gene; FCH; Fold change; HI; High infl
Atopic dermatitis and skin diseaseThe Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization
Keywords: Atopic dermatitis; TH1; TH2; TH17; TH22; acanthosis; parakeratosis; psoriasis; Asian; European American; AD; Atopic dermatitis; DC; Dendritic cell; EA; European American; FCH; Fold change; FLG; Filaggrin; IHC; Immunohistochemistry; LC; Langerhans cell; PC
Berberine ameliorates TNBS induced colitis by inhibiting inflammatory responses and Th1/Th17 differentiation
Keywords: Crohn's disease; Inflammatory bowel disease; Berberine; Th1; Th17;
IFN-β inhibits T cells accumulation in the central nervous system by reducing the expression and activity of chemokines in experimental autoimmune encephalomyelitis
Keywords: EAE; IFN-β; Chemokine; Chemokine receptors; Th1; Th17;
Dehydrodiconiferyl alcohol (DHCA) modulates the differentiation of Th17 and Th1 cells and suppresses experimental autoimmune encephalomyelitis
Keywords: Dehydrodiconiferyl alcohol (DHCA); Th17; Th1; IL-17; RORγt; NF-κB; EAE
Melatonin controls experimental autoimmune encephalomyelitis by altering the T effector/regulatory balance
Keywords: BBB; blood-brain barrier; dLN; draining lymph nodes; EAE; experimental autoimmune encephalomyelitis; HA; hyaluronan; MFI; median fluorescence intensity; MLT; melatonin; MS; multiple sclerosis; 6-SMT; 6-sulphatoxymelatonin; TCM; T central memory cells; T
Platycodon grandiflorus - An Ethnopharmacological, phytochemical and pharmacological review
Keywords: (2R, 3R) taxifolin (Pubchem CID: 439533); quercetin-7-O-glucoside (Pubchem CID: 5282160); luteolin-7-O-glucoside (Pubchem CID: 5280637); apigenin-7-O-glucoside (Pubchem CID: 5280704); luteolin (Pubchem CID: 5280445); apigenin (Pubchem CID: 5280443); palmi
Structure based 3D-QSAR studies of Interleukin-2 inhibitors: Comparing the quality and predictivity of 3D-QSAR models obtained from different alignment methods and charge calculations
Keywords: CCBSA; co-crystallized-maximum common structure based alignment; CoMFA; Comparative Molecular Field Analysis; CoMSIA; Comparative Molecular Similarity Indices Analysis; GALAHAD; Genetic Algorithm with Linear Assignment of Hyper-molecular Alignment of Data
HAMI 3379, a CysLT2R antagonist, dose- and time-dependently attenuates brain injury and inhibits microglial inflammation after focal cerebral ischemia in rats
Keywords: Blood-brain barrier; BBB; CSF; cerebrospinal fluid; CysLT1R; cysteinyl leukotriene receptor 1; CysLT2R; cysteinyl leukotriene receptor 2; CysLTs; cysteinyl leukotrienes; DMSO; dimethyl sulfoxide; GFAP; glial fibrillary acidic protein; Iba-1; ionized cal
Mesenchymal Stem Cells Reduce Colitis in Mice via Release of TSG6, Independently of Their Localization to the Intestine
Keywords: Experimental Models of Colitis; IBD; Immune Regulation; Mesenchymal Stem Cell-Based Therapy; A-MSC; adipose-derived mesenchymal stem cell; BM; bone marrow; BM-MSC; bone marrow-derived mesenchymal stem cell; DSS; dextran sodium sulfate; GFP; green fluore
Litchi chinensis: medicinal uses, phytochemistry, and pharmacology
Keywords: Aq; aqueous; A549; human lung cancer; ABTS; 2,2â²-Azinobis(3-ethylbenzothiazoline-6-sulfonate); ADP; adenosine diphosphate; AGS; human gastric epithelial; ADPRTL1; ADP-ribosyltransferase (NAD+poly (ADP-ribose) polymerase)-like 1); ADAM9; metalloproteinas
Decreased Tim-3 and its correlation with Th1 cells in patients with immune thrombocytopenia
Keywords: Immune thrombocytopenia; T-cell immunoglobulin- and mucin- domain-containing molecule 3; Th1; T-bet;
Identification of hepatitis B virus-specific CTL epitopes presented by HLA-Aâ33:03 in peripheral blood mononuclear cells from patients and transgenic mice
Keywords: AHB; acute hepatitis B; CHB; chronic hepatitis B; CTL; cytotoxic T lymphocyte; ELISPOT; enzyme-linked immunospot; HBV; hepatitis B virus; HC; HLA heavy chain; HLA; human leukocyte antigen; IFN-γ; interferon-γ; PBMC; peripheral blood mononuclear cell; TH
Effect of Estrogen on Th1, Th2 and Th17 Cytokines Production by Proteolipid Protein and PHA Activated Peripheral Blood Mononuclear Cells Isolated from Multiple Sclerosis Patients
Keywords: Estrogen; Multiple sclerosis; 17-β estradiol; Th1; Th2; Th17; Regulatory T cells
Analysis of Th1, Th17 and regulatory T cells in tuberculosis case contacts
Keywords: TB; tuberculosis; MTB; Mycobacterium tuberculosis; TST; tuberculin skin test; IGRAs; interferon-γ release assays; PPD; purified protein derivative; IFN-γ; interferon-γ; Treg; T regulatory; Foxp3; forkhead box P3; CTLA-4; cytotoxic T-lymphocyte antigen
Recombinant BCG coexpressing Ag85B, ESAT-6 and Rv3620c elicits specific Th1 immune responses in C57BL/6 mice
Keywords: Mycobacterium tuberculosis; rBCG; Th1; Cytokines; Vaccine
Screening and identification of T helper 1 and linear immunodominant antibody-binding epitopes in spike 1 domain and membrane protein of feline infectious peritonitis virus
Keywords: Coronavirus; Feline infectious peritonitis; Th1; Peptide-based vaccine;
Clinical, molecular, and T cell subset analyses in a small cohort of Chinese patients with hyper-IgM syndrome type 1
Keywords: HIGM1; CD40L; Th1; Th17; Treg
IL-12 secretion by Langerhans cells stimulated with Candida skin test reagent is mediated by dectin-1 in some healthy individuals
Keywords: Interleukin-12; Dectin-1; Candida; T-cell; Th1;
Effects of Th1 and Th2 cells balance in pulmonary injury induced by nano titanium dioxide
Keywords: Nano TiO2; Immune response; Th1; Th2; Pulmonary injury
Frequency of Chlamydia trachomatis-specific T cell interferon-γ and interleukin-17 responses in CD4-enriched peripheral blood mononuclear cells of sexually active adolescent females
Keywords: Immunity; Antigen; Genital; Pelvic inflammatory disease; Th1; Th17
Modeling the effects of covalently closed circular DNA and dendritic cells in chronic HBV infection
Keywords: HBV; Hepatitis B virus; CccDNA; Covalently closed circular DNA; DCs; Dendritic cells; IFN; Interferon alpha; NAs; Nucleoside/nucleotide analogs; APCs; Antigen-presenting cells; CTL; Cytotoxic T lymphocyte; Th1; Helper T cell 1; HBsAg; HBV surface antigen;
Frequency of regulatory T-cell and hepatitis C viral antigen-specific immune response in recurrent hepatitis C after liver transplantation
Keywords: ALT; alanine aminotransferase; CHC; chronic hepatitis C; DC; dendritic cell; ELISPOT; enzyme-linked immunosorbent spot; FITC; fluorescein isothiocyanate; FOXP3; forkhead box P3; HCV; hepatitis C virus; IL; interleukin; IFN; interferon; LPS; lipopolysaccha
A TB Antigen-Stimulated CXCR3 Ligand Assay for the Diagnosis of Active Pulmonary TB
Keywords: AUC; area under the curve; CXCR3; CXC chemokine receptor 3; IFN; interferon; IGRA; interferon-γ release assay; IP-10; interferon-γ-inducible 10-kDa protein; I-TAC; interferon-inducible T-cell α-chemoattractant; LTBI; latent TB infection; MIG; monokine
Distinct from its canonical effects, deletion of IL-12p40 induces cholangitis and fibrosis in interleukin-2Rαâ/â mice
Keywords: IL-12p40; Primary biliary cirrhosis; Fibrosis; IFN-γ; Effector memory cells; ALT; serum alanine aminotransferase; ANOVA; one-way analysis of variance; CCL2; chemokine (C-C motif) ligand 2; dnTGFβRII; dominant negative form of transforming growth facto
SPA0355 suppresses T-cell responses and reduces airway inflammation in mice
Keywords: AHR; airway hyperresponsiveness; BAL; bronchoalveolar lavage; BALF; BAL fluid; CD; cluster of differentiation; CFSE; carboxyfluorescein succinimidyl ester; CsA; cyclosporine A; ERK; extracellular signal-regulated kinase; GADPH; glyceraldehyde-3-phosphate
Effect and mechanisms of curdlan sulfate on inhibiting HBV infection and acting as an HB vaccine adjuvant
Keywords: Curdlan sulfate; Anti-HBV; HBsAg; Th1; Vaccine adjuvant
Therapeutic efficacy of the multi-epitope vaccine CTB-UE against Helicobacter pylori infection in a Mongolian gerbil model and its microRNA-155-associated immuno-protective mechanism
Keywords: Hp; Helicobacter pylori; Th1; Type 1 of helper T lymphocyte; Th2; Type 2 of helper T lymphocyte; NC; normal control group; MC; model control group; PC; positive control group; HD; high-dose group; MD; middle-dose group; LD; low-dose group; IFN-γ; interfe
Application of pH-sensitive fusogenic polymer-modified liposomes for development of mucosal vaccines
Keywords: Fusogenic liposomes; Mucosal vaccines; Protective immunity; Th1; Salmonella Enteritidis;
Effector molecules released by Th1 but not Th17 cells drive an M1 response in microglia
Keywords: Microglia; Th1; Th17;
Local hyperthermia treatment of tumors induces CD8+ T cell-mediated resistance against distal and secondary tumors
Keywords: IONP; iron oxide nanoparticle; AMF; alternating magnetic field; DC; dendritic cell; dLN; draining lymph node; HSP; heat-shock protein; APC; antigen presenting cell; ID; intradermally; CEM; cumulative equivalent minutes at 43°C; SEM; standard error of the
Human leukocyte antigen (HLA)-G and cervical cancer immunoediting: A candidate molecule for therapeutic intervention and prognostic biomarker?
Keywords: 3â²UTR; untranslated region; 5â²URR; upstream regulatory region; ADC; cervical adenocarcinoma; AGUS; atypical glandular cells; APC; antigen presenting cells; ATG; start codon; Cd; cytoplasmatic domain; CD; cluster of differentiation; CIN; cervical intra
SOCS3 and STAT3, major controllers of the outcome of infection with Mycobacterium tuberculosis
Keywords: Arg1; arginase 1; Bcl6; B cell lymphoma 6; CD; cluster of differentiation; CXC; C-X-C motif chemokine; CARD9; caspase recruitment domain-containing protein 9; CISH; cytokine-inducible SH2-containing protein; DC; dendritic cell; DC-SIGN; DC-specific interc
IFN-γ suppresses permissive chromatin remodeling in the regulatory region of the Il4 gene
Keywords: IFN-γ; Th1; Silencing Il4 gene expression; Chromatin remodeling;
Short CommunicationInterleukin-10 prevents epithelial cell apoptosis by regulating IFNγ and TNFα expression in rhesus macaque colon explants
Keywords: AC-3; active caspase-3; IL-10; interleukin-10; HIV; human immunodeficiency virus; Th1; T-helper 1; JAK1; janus kinase 1; Tyk2; tyrosine kinase 2; SCID; severe combined immunodeficiency; EC; epithelial cells; RM; rhesus macaque; MAb; monoclonal antibody; r