Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10085 | Biomaterials | 2009 | 7 Pages |
Abstract
HER2 detection is important for breast cancer (BC) treatment and prognosis, but the detection methods currently used have some disadvantages. Quantum dots (QDs)-based probes provide a potentially important new method for HER2 detection in clinical practice. This potential is examined in this paper. A QDs HER2 probe kit and QDs image acquisition and analysis software were developed and applied to 94 clinical samples of BC. Compared to conventional immunohistochemistry techniques, this method provided a superior accurate and sensitive method for the detection of HER2 in clinical breast cancer diagnosis.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Chuang Chen, Jun Peng, He-Shun Xia, Gui-Fang Yang, Qiong-Shui Wu, Liang-Dong Chen, Li-Bo Zeng, Zhi-Ling Zhang, Dai-Wen Pang, Yan Li,