• Daneshyari
  • Topics
    • Physical Sciences and Engineering
      Life Sciences
      Health Sciences
      Social Sciences and Humanities
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery

Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data

Article ID Journal Published Year Pages File Type
10129302 European Journal of Pharmaceutical Sciences 2018 37 Pages PDF
Keywords
PBPKAAGIn vitro-in vivo extrapolationIVIVEIPRLα1-Acid glycoproteinPharmacokineticsPharmacokinetic(s)Well-stirred modelDispersion modelIntrinsic clearanceHepatic clearanceIsolated perfused rat liver
Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery
Preview
Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data
Authors
Jin Dong, Miki Susanto Park,
Related Articles
Experiment and DFT studies on radioiodine removal and storage mechanism by imidazolium-based ionic liquid
Contribution of main chain and side chain atoms and their locations to the stability of thermophilic proteins
Crystal morphology prediction of 1,3,3-trinitroazetidine in ethanol solvent by molecular dynamics simulation
Design and synthesis of a novel class of carbonic anhydrase-IX inhibitor 1-(3-(phenyl/4-fluorophenyl)-7-imino-3H-[1,2,3]triazolo[4,5d]pyrimidin 6(7H)yl)urea
Quantitative structure–hydrophobicity relationships of molecular fragments and beyond
Cationic P⋯N interaction in XH3P+⋯NCY complexes (X = H, F, CN, NH2, OH; Y = H, Li, F, Cl) and its cooperativity with hydrogen/lithium/halogen bond
Ion–π interaction in impacting the nonlinear optical properties of ion–buckybowl complexes
RADMAP: Simple probes for rapid assessment of complex reactivity: A method and case studies on the reaction of hydrogen atoms with unsaturated organic molecules
Development and targeting of transcriptional regulatory network controlling FLU1 activation in Candida albicans for novel antifungals
Thermo-mechanical properties of boron nitride nanoribbons: A molecular dynamics simulation study
Journal
European Journal of Pharmaceutical Sciences
Journal: European Journal of Pharmaceutical Sciences
Related Categories
PBPK
AAG
In vitro-in vivo extrapolation
IVIVE
IPRL
α1-Acid glycoprotein
Pharmacokinetics
Pharmacokinetic(s)
Well-stirred model
Dispersion model
Intrinsic clearance
Hepatic clearance
Isolated perfused rat liver
Drug Discovery
Pharmaceutical Science
Pharmacology
Pharmacology, Toxicology and Pharmaceutics (General)
Toxicology
Related Journals
Journal of Molecular Graphics and Modelling
Nanomedicine: Nanotechnology, Biology and Medicine
EuPA Open Proteomics
Journal of the American Society for Mass Spectrometry
Tetrahedron: Asymmetry
Bioorganic Chemistry
Bioorganic & Medicinal Chemistry
Bioorganic & Medicinal Chemistry Letters
European Journal of Medicinal Chemistry
Phytochemistry Letters
Tetrahedron
Tetrahedron Letters
Translational Proteomics
Biosystems
Drug Discovery Today
Drug Discovery Today: Disease Mechanisms
Drug Discovery Today: Disease Models
Drug Discovery Today: Technologies
Drug Discovery Today: Therapeutic Strategies
Nuclear Medicine and Biology
Update on Cancer Therapeutics
Procedia in Vaccinology
Acta Pharmaceutica Sinica B
Daneshyari provides fulltext access to millions of research papers.