Acridone alkaloids from the stem bark of Citrus aurantium display selective cytotoxicity against breast, liver, lung and prostate human carcinoma cells

Article ID	Journal	Published Year	Pages	File Type
10143318	Journal of Ethnopharmacology	2018	34 Pages	PDF

Keywords

A549 DCM IC50 MCF7 Citrus aurantium HSQC PC3 NOESY ECACC ATCC Rutaceae n-Hex CDCl3 high resolution electrospray ionization mass spectrometry Stock solution VLC distortionless enhancement by polarisation transfer HMBC PBS HepG2 FBS NCI nuclear magnetic resonance 50% inhibitory concentration DMSO m/z MTT n-Hexane Nuclear Overhauser Effect SpectroscopY Human lung adenocarcinoma human breast adenocarcinoma acridone alkaloids ANOVA one-way analysis of variance NMR standard error of mean Dichloromethane Dimethyl sulfoxide World Health Organisation foetal bovine serum selectivity index Ultraviolet spectroscopy Infra-red spectroscopy correlated spectroscopy phosphate buffered-saline Methanol American Type Culture Collection SEM National Cancer Institute MeOH mass to charge ratio Hertz heteronuclear multiple bond correlation optical density COSY Column chromatography high performance liquid chromatography Vacuum liquid chromatography HPLC Chloroform WHO

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Acridone alkaloids from the stem bark of Citrus aurantium display selective cytotoxicity against breast, liver, lung and prostate human carcinoma cells

Authors

Peter A. Segun, Fyaz M.D. Ismail, Omonike O. Ogbole, Lutfun Nahar, Andrew R. Evans, Edith O. Ajaiyeoba, Satyajit D. Sarker,