Development of an effective and safe topical anti-inflammatory gel containing Jatropha gossypiifolia leaf extract: Results from a pre-clinical trial in mice

Article ID	Journal	Published Year	Pages	File Type
10143347	Journal of Ethnopharmacology	2018	25 Pages	PDF

Keywords

Thiolate TNB PGE2 iNOS DTNB Euphorbiaceae CONCEA TBARS Jatropha gossypiifolia tPA PKC 5-LOX CIOMS Mitogen-activated kinases COX MDA TNF PBS PLA2 NF-κB HPLC-DAD AP-1 5-Lipoxygenase 5,5′-dithiobis(2-nitrobenzoic acid)MPO MAPK ROS cyclooxygenase phospholipase A2 EDTA Ear edema Arachidonic acid ethylenediamine tetraacetic acid interleukin analysis of variance ANOVA standard error of mean Retention time inducible nitric oxide synthase Platelet activating factor tumor necrosis factor nuclear factor kappa B ultra-violet Phosphate buffered saline activating protein-1 Antioxidant activity malondialdehyde SEM thiobarbituric acid reactive substances myeloperoxidase Nitric oxide PAF Protein kinase C Prostaglandin E2 high-performance liquid chromatography with diode array detection Reactive oxygen species

Related Topics

Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology

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Development of an effective and safe topical anti-inflammatory gel containing Jatropha gossypiifolia leaf extract: Results from a pre-clinical trial in mice

Authors

Jacinthia B. Xavier-Santos, Juliana Félix-Silva, Júlia G.R. Passos, Jacyra A.S. Gomes, Júlia M. Fernandes, VinÃcius Barreto Garcia, Raimundo Fernandes de Araujo-Junior, Silvana M. Zucolotto, Arnóbio A. Silva-Junior, Matheus F. Fernandes-Pedrosa,