Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10148717 | Microbial Pathogenesis | 2018 | 22 Pages |
Abstract
Low cost and an easy technique for the synthesis of palladium nanoparticles (PdNPs) was developed. Glucosamine was used to stabilize palladium precursor (PdCl2) into palladium nanoparticles. Several analytical techniques were used for the determination of morphology, crystalline structure; size, capping, and composition of synthesize palladium nanoparticles. The UV-visible spectroscopy SPR peak (Surface Plasmon Resonance) at 284â¯nm revealed synthesis of PdNPs. Energy dispersive X-ray (EDX) and X-ray diffraction (XRD) studies proved the elemental composition and crystalline structure of the synthesized palladium nanoparticles respectively. The average particle sizes (5.5â¯nm) were obtained by using the 1â¯M glucosamine solution, with a fixed amount of PdCl2 (4â¯mM). Moreover, the as synthesized PdNPs was evaluated against Gram negative bacterial E. which shows tremendous antibacterial activity as compare to tobramycin standard antibiotics. It's mechanistically found that PdNPs damage cell membrane and caused imbalance of metabolism system of the cell as a result production of reactive oxygen species (ROS). Thus, these finding revealed that cells become leaky and all organelles come out from cells, finally caused death of the E. coli. Addition, the as prepared PdNPs also showed excellent catalytic activities toward reduction of methylene blue and 4-nitrophenol.Thus, glucosamine mediated PdNPs having dual functions biomedical as well as intoxicating catalyst for industries.
Keywords
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Authors
Sadeeq Ullah, Aftab Ahmad, Arifullah Khan, Jie Zhang, Muslim Raza, Aziz ur Rahman, Muhammad Tariq, Usman Ali khan, Shah Zada, Qipeng Yuan,