Article ID Journal Published Year Pages File Type
10157029 Steroids 2018 27 Pages PDF
Abstract
Our findings demonstrate that LPCs with saturated acyl groups induce the expression of genes involved in cholesterol biosynthesis and may have implications for cholesterol related diseases.
Keywords
Akt3LSSDHCR24KLF4FPKMHsd17b7ACAT2CYP27A1FADS2DHCR77-dehydrocholesterol reductaseHMGCS1KLF2RNA profilingMVKANKRD1TM7SF2Krüppel like factor 4fragments per kilobase of transcript per million fragments mappedCYP51A1ankyrin repeat domain 1Kruppel like factor 2Mevalonate diphosphate decarboxylaseKEGGNOS2GAPDHRT-PCRFFASCDHMGCRSREBP-2LPCMVDstearoyl-CoA desaturaseATF3LPAEGR124-dehydrocholesterol reductase3-hydroxy-3-methylglutaryl-CoA reductaseDMSOPCAlysophosphatidic acidfatty acid desaturase 2Free fatty acidsPrincipal component analysisKyoto Encyclopedia of Genes and GenomesDimethyl sulfoxideSterol regulatory element-binding protein-2activating transcription factor 3Lanosterol synthaseLysophosphatidylcholinenitric oxide synthase 2reverse transcription polymerase chain reactionearly growth response 1Mevalonate Kinaseglyceraldehyde-3-phosphate dehydrogenase
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Lysophosphatidylcholine induces expression of genes involved in cholesterol biosynthesis in THP-1 derived macrophages
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