Article ID Journal Published Year Pages File Type
10159005 Acta Biomaterialia 2014 12 Pages PDF
Abstract
Conjugation of ATF with zinc phthalocyanine (ZnPc) renders ZnPc soluble in water and generates a conjugate highly specific to uPAR-abundant tumor cells. ATF-ZnPc preferentially accumulates in lysosome organelle, mainly through uPA receptor-dependent endocytosis, and induces cell death upon light illumination.148
Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
Authors
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