Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10159199 | Acta Biomaterialia | 2014 | 12 Pages |
Abstract
Amphiphilic hyaluronic acid-poly(l-histidine) (HA-PHis) copolymer was designed for use as a tumor targeted and pH-sensitive nanocarrier for intracellular delivery of doxorubicin. After CD44 receptor-mediated cellular uptake, doxorubicin was released rapidly in an intracellular low pH environment.169
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Lipeng Qiu, Zhen Li, Mingxi Qiao, Miaomiao Long, Mingyue Wang, Xiaojun Zhang, Chenmin Tian, Dawei Chen,