| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10159324 | Acta Biomaterialia | 2014 | 10 Pages |
Abstract
2-Hydroxyethyl methacrylate (HEMA) and 2-hydroxyethyl acrylate (HEA) were respectively used to modify a kind of amphiphilic cationic nanoparticles to change their external hydrophilicity. The hydrophilic/hydrophobic modifications significantly influenced the gene transfection efficiency of these nanoparticles in vitro, due to different cellular uptake and endosomal escape efficacy.
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Authors
Shangcong Han, Haiying Wan, Daoshu Lin, Shutao Guo, Hongxu Dong, Jianhua Zhang, Liandong Deng, Ruming Liu, Hua Tang, Anjie Dong,