Article ID Journal Published Year Pages File Type
10161185 Biochemical Engineering Journal 2005 16 Pages PDF
Abstract
Comparing the proposed model with experimental elution curves obtained at different salt concentrations, it is proposed that the effective protein charge could depend upon the salt concentration (or ionic strength). The reason for this dependence may be a steric hindrance of protein binding sites combined with a salt shielding effect neutralizing the surface charges of the protein.
Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
Authors
, , ,