Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10162049 | Journal of Pharmaceutical Sciences | 2015 | 7 Pages |
Abstract
Current industry perspective of how discovery is conducted seems to be fragmented and does not have a unified overall outlook of how discovery challenges are being addressed. Consequently, well-defined processes and drug-likeness criteria are being viewed as “broken” and will not maintain future R&D productivity. In this commentary, an analysis of existing practices for defining successful development candidates resulted in a 5 “must do” list to help advance Drug Discovery as presented from a Pharmaceutics perspective. The 5 “must do” list includes: what an ideal discovery team model should look like, what criteria should be considered for the desired development candidate profile, what the building blocks of the development candidate should look like, and how to assess the development risks of the candidate. © 2014 Wiley Periodicals, Inc. and the American Pharmacists Association.
Keywords
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Elizabeth Kwong,