Rola terapii biologicznej w podtrzymaniu remisji u dzieci z chorobÄ Leśniowskiego i Crohna

In recent years there has been an increase in the incidence of inflammatory bowel disease including Crohn's disease in children. The aim of treatment of Crohn's disease is the induction and maintenance of remission. Currently, it is believed that to achieve healing of the intestinal mucosa may be synonymous with getting complete remission and inhibition of disease progression. Biologics and immunomodulators have a definite place in the treatment of Crohn disease. However, there are no clear guidelines on the efficacy and safety of these two classes of drugs for the children treatment. In addition, questions about the safety of long-term use of biological drugs as well as the best moment of their inclusion needs further reaserch.