Alergia pokarmowa IgG-zależna i jej znaczenie w wybranych jednostkach chorobowych

The development of allergy process is caused by the negative influence of various factors on human organism. The reason for food allergy in a predisposed group of people is immunological mechanisms, which are classified in four types (according to Gell-Coombs). It is said that 50% of food allergy reaction is caused by IgE-dependent mechanism (immediate reaction). In the remaining group it is a retarded reaction (IgE-independent) or mixed (IgE-independent and IgE-dependent). It is claimed that an increase in the level of antibodies against particular food allergens could be one of reasons behind the development of the gastrointestinal symptoms. It should be emphasized that the role of IgG-dependent allergy is still being discussed and the results of research are inconclusive. Yet, there are analyses which show that an elimination diet based on the results of the study of specific IgG antibodies against the food antigens is beneficial in treatment of IBS, IBD and psychiatric disorders. That is why the authors of the above analysis decided to review the current data concerning the effectiveness of a diet based on the results of IgG-dependent allergy research in reducing the symptoms of particular health problems.