| Article ID | Journal | Published Year | Pages | File Type | 
|---|---|---|---|---|
| 10172190 | Respiratory Investigation | 2013 | 9 Pages | 
Abstract
												Approximately 60% of smokers were shown to exhibit apparent impedance changes despite having normal FEV1/FVC values. Smoking-induced early remodeling of the small airways may be responsible for the observed changes in airway function of smokers. Further studies are necessary to determine if the change in respiratory impedance observed in smokers is an early indicator of COPD.
											Keywords
												RRSFOTFresR20XRSZrsPFTrespiratory reactanceICSFEV13-dimensionalLAMARespiratory impedancelong-acting beta-agonistChronic obstructive pulmonary diseaseCOPDSmall airway diseasePulmonary function testForced oscillation techniqueForced expiratory volume in 1 sSmokerLABARespiratory resistanceInhaled corticosteroids
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											Authors
												Haruko Shinke, Masatsugu Yamamoto, Nobuko Hazeki, Yoshikazu Kotani, Kazuyuki Kobayashi, Yoshihiro Nishimura, 
											