| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10230105 | Biomaterials | 2005 | 9 Pages |
Abstract
It was observed that melt compression and melt extrusion are feasible techniques to prepare the nerve guides. Based on the physicochemical characterization, all samples show absence of crystalline sabeluzole, indicating the formation of an amorphous dispersion. The in vitro release measurements show that the release of sabeluzole is complete, reproducible and can be controlled by the proper selection of the polymer. The release mechanism for all samples follows Fickian release behaviour.
Keywords
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Geert Verreck, Iksoo Chun, Yufu Li, Ram Kataria, Qiang Zhang, Joel Rosenblatt, Annelies Decorte, Koen Heymans, Jef Adriaensen, Monique Bruining, Marie Van Remoortere, Herman Borghys, Theo Meert, Jef Peeters, Marcus E. Brewster,