| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10230316 | Biomaterials | 2005 | 12 Pages |
Abstract
In conclusion, absence of microfibrils from the elastic fibre does not prevent calcification in young Sprague Dawley rats, but does reduce the tissue response in adult Wistar rats. Cellular response and calcification differs with age and strain and therefore the choice of animal model is of key importance in biomaterial evaluation.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
W.F Daamen, S.T.M Nillesen, T Hafmans, J.H Veerkamp, M.J.A van Luyn, T.H van Kuppevelt,