| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10231896 | Computational Biology and Chemistry | 2011 | 10 Pages |
Abstract
⺠In this work we built a 3D model of the human receptor OR 17-40. ⺠The amino acids lining the putative binding pocket were identified. ⺠We investigated the binding ability of a set of odorous molecules by docking simulations. ⺠The olfactory and electrophysiological properties of new ligands synthesised were tested. ⺠Results indicate that several factors are involved in the ligand/OR 17-40 interaction.
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Authors
Cecilia Anselmi, Anna Buonocore, Marisanna Centini, Roberto Maffei Facino, Hanns Hatt,