Article ID Journal Published Year Pages File Type
10231911 Computational Biology and Chemistry 2011 11 Pages PDF
Abstract
► We compared two linear gap penalties with two profile-based gap penalties. ► We examine alignment accuracy improvements brought by profile-based gap penalties. ► Profile-based gap penalties get limited improvements than linear gap penalties. ► Secondary structure is less powerful in gap penalties than in scoring functions. ► The maximal potential of the indel frequency profiles remains to be discovered.
Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
Authors
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