Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10231911 | Computational Biology and Chemistry | 2011 | 11 Pages |
Abstract
⺠We compared two linear gap penalties with two profile-based gap penalties. ⺠We examine alignment accuracy improvements brought by profile-based gap penalties. ⺠Profile-based gap penalties get limited improvements than linear gap penalties. ⺠Secondary structure is less powerful in gap penalties than in scoring functions. ⺠The maximal potential of the indel frequency profiles remains to be discovered.
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Bioengineering
Authors
Chuan Wang, Ren-Xiang Yan, Xiao-Feng Wang, Jing-Na Si, Ziding Zhang,