Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10232110 | Current Opinion in Biotechnology | 2013 | 10 Pages |
Abstract
- Novel molecular tools advance the productivity of engineered multi-enzyme biochemical pathways in live cells.
- These tools enable precise, rapid pathway construction and static and dynamic control of enzyme expression levels.
- Molecular tools facilitate enzyme or pathway optimization via directed evolution and systems biology approaches.
- The generalizability of each tool depends on its function, context dependence, and host requirements.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Stephanie Galanie, Michael S Siddiqui, Christina D Smolke,