| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10232132 | Current Opinion in Biotechnology | 2013 | 8 Pages |
Abstract
- Proliferating mammalian cultures exhibit 'wasteful' glucose and glutamine metabolism.
- Stationary cultures shift to oxidative phosphorylation and reduce lactate production.
- Metabolism is regulated dynamically by expression and activation of enzymes.
- Metabolic flux analysis provides a global picture of dynamic flux rewiring.
- Metabolic engineering can be applied to redirect cells toward desired phenotypes.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Jamey D Young,