Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10232260 | Current Opinion in Biotechnology | 2011 | 9 Pages |
Abstract
⺠Several biosynthetic pathways have been recently engineered in E. coli or S. cerevisiae to produce advanced biofuels. ⺠The advanced biofuels include alcohols, terpenes, fatty acid alkyl esters, alkanes, and alkenes. ⺠Many of the advanced biofuels were converted from simple sugars with high titers and yields. ⺠It is advantageous to use native high flux pathways to provide key precursors for fuel molecule biosynthesis. ⺠Limiting the use of precursors by competing pathways can increase flux toward product. ⺠Creating irreversible steps in the engineered pathway may be beneficial for biofuel production.
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Physical Sciences and Engineering
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Authors
Fuzhong Zhang, Sarah Rodriguez, Jay D Keasling,