| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10232271 | Current Opinion in Biotechnology | 2011 | 10 Pages |
Abstract
⺠Several aglycosylated IgGs have been developed and are in clinical trials. ⺠Aglycosylated antibodies can be produced with high yields in bacteria. ⺠Aglycosylated antibody expression eliminates glycan heterogeneity. ⺠Engineered aglycosylated antibodies can display novel therapeutic effector functions.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Sang Taek Jung, Tae Hyun Kang, William Kelton, George Georgiou,