Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10232499 | Current Opinion in Biotechnology | 2005 | 4 Pages |
Abstract
The development of contrast agents that can be localized to a particular tissue or cellular epitope will potentially allow the noninvasive visualization and characterization of a variety of disease states. Recent advances have been made in the field of molecular imaging with magnetic resonance imaging and ultrasound and varied approaches have been devised to overcome the high background tissue signal. The types of agents and applications developed include gadolinium-conjugated targeting molecules for imaging of fibrin, superparamagnetic iron oxide particles for stem-cell tracking, multimodal perfluorocarbon nanoparticles for visualization of angiogenesis, liposomes for targeting atheroma components, and microbubbles for imaging transplant rejection.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Anne M Morawski, Gregory A Lanza, Samuel A Wickline,