| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10234595 | Metabolic Engineering | 2012 | 14 Pages |
Abstract
⺠A constraint-based model of yeast fermentation was developed and used to study NADPH homeostasis. ⺠The NADPH demand was increased to between 8 and 40-fold the anabolic demand. ⺠At moderate NADPH demand the PP and acetate pathways provide 80% and 20% of the NADPH demand. ⺠At high NADPH demand, the model predicts additional NADPH production from NADH by the glycerol-DHA futile cycle.
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Authors
Magalie Celton, Anne Goelzer, Carole Camarasa, Vincent Fromion, Sylvie Dequin,