Article ID Journal Published Year Pages File Type
10234596 Metabolic Engineering 2012 8 Pages PDF
Abstract
► Engineering of Escherichia coli cells expressing acyl-ACP thioesterase with glucose yield higher than 40% of theoretical yield. ► Deletion of metabolic pathways leading to acetate accumulation changes the fatty acid compositions but not the fatty acid production. ► Marked reduction in acetate accumulation for high fatty acid producing strains. ► Significant increase in extracellular fatty acids accumulation for strains bearing the long chain fatty acid CoA-ligase (fadD) mutation.
Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
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