| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10234600 | Metabolic Engineering | 2012 | 15 Pages |
Abstract
⺠Identification of sphingolipid biosynthesis genes in P. ciferrii. ⺠Isolation of a syringomycin-resistant strain producing predominantly sphinganine. ⺠Construction of an efficient sphingosine-producing P. ciferrii strain. ⺠Production of 0.9 g acetylated sphingosine per liter in lab-scale fermentation. ⺠Suppression of by-product formation by inactivating the SLD1 gene.
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Authors
Daniel Börgel, Marco van den Berg, Thomas Hüller, Heiko Andrea, Gerhard Liebisch, Eckhard Boles, Christoph Schorsch, Ruud van der Pol, Anne Arink, Ilco Boogers, Rob van der Hoeven, Kees Korevaar, Mike Farwick, Tim Köhler, Steffen Schaffer,