Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10235067 | New Biotechnology | 2013 | 6 Pages |
Abstract
⺠RNA interference is a dsRNA-mediated silencing mechanism operating in eukaryotes. ⺠RNAi allows to systematically evaluate gene function in a genome-wide manner. ⺠RNAi screens provide a rich source of functional data for follow-up studies. ⺠RNAi is sensitive to off-target effects and cell population context. ⺠RNAi technology for biomedical applications has advanced to clinical trials.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Simone C Eicher, Christoph Dehio,