| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10235264 | Process Biochemistry | 2015 | 9 Pages |
Abstract
- Direct applicability of mid infrared spectroscopy to in situ samples of downstream processing is shown.
- Possibility to monitor different critical quality attributes.
- Applicable to different steps of purification cascade.
- Quantification possible down to: 1% [w/w] aggregates, 700 ng mlâ1 HCP, 0.7 g Lâ1 mAb.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Florian Capito, Romas Skudas, Harald Kolmar, Christian Hunzinger,