Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10235536 | Process Biochemistry | 2019 | 8 Pages |
Abstract
⺠2,5-Diketo-gluconic acid (2,5-DKG) reductase activity was found in 9 bacterial strains. ⺠2,5-DKG reductase synthesizes the immediate precursor of vitamin C. ⺠Corynebacterium glutamicum 2,5-DKG reductase was expressed in high yield and characterized. ⺠The catalytic mechanism and inhibition kinetics were elucidated to guide enzyme and process engineering.
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Authors
Vanja Kaswurm, Claudia Pacher, Klaus Dieter Kulbe, Roland Ludwig,