Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10235556 | Process Biochemistry | 2012 | 7 Pages |
Abstract
⺠We overexpressed fumarase encoded by fumR in Rhizopus oryzae. ⺠The transformants showed 5-10-fold increase in fumarase activity compared to the wild type. ⺠The effect of overexpressing fumR on fumaric acid production was investigated. ⺠Fumarase overexpression yielded more malic acid, instead of fumaric acid, in the fermentation. ⺠This is because the fumarase also catalyzes the hydration of fumaric acid to malic acid.
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Authors
Baohua Zhang, Shang-Tian Yang,