Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10235559 | Process Biochemistry | 2012 | 7 Pages |
Abstract
⺠C. koseri cells catalyzed the transglycosylation of arabinonucleosides. ⺠Fludarabine, vidarabine and diaminopurine arabinoside were obtained in good yields. ⺠Different entrapment immobilizations and reactor configurations were assayed. ⺠C. koseri immobilized in agarose could be used up to 68 times. ⺠150 mL scale reaction afforded vidarabine in 71.2% yield.
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Authors
MatÃas Nóbile, Rosario Médici, Marco Terreni, Elizabeth S. Lewkowicz, Adolfo M. Iribarren,