Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10235712 | Process Biochemistry | 2012 | 9 Pages |
Abstract
⺠3-HP production from glycerol by K. pneumoniae is dependent on the activity of ALDH. ⺠KGSADH was the most efficient enzyme in 3-HP production among the ALDHs used here. ⺠To enhance 3-HP production, competing enzymes, DhaT and NADPH-HOR were eliminated. ⺠dhaT gene deletion had a significant effect on 3-HP production than yqhD deletion. ⺠DhaT is the major enzyme, which is involved in 1,3-PDO production by K. pneumoniae.
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Authors
Yeounjoo Ko, Somasundar Ashok, Shengfang Zhou, Vinod Kumar, Sunghoon Park,