| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10235812 | Process Biochemistry | 2013 | 12 Pages |
Abstract
⺠Dynamic reaction-diffusion modeling applied to immobilized cephalosporin C amidase. ⺠First time model parameter estimation to in situ measured real-time intraparticle pH data. ⺠Model-based estimates of intrinsic immobilized enzyme activity and effective proton diffusion coefficient. ⺠Correlation of intraparticle pH and concentration gradients with immobilized enzyme effectiveness. ⺠Model-based optimization of carrier properties for immobilization design.
Keywords
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Physical Sciences and Engineering
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Bioengineering
Authors
Thomas Zahel, Caterina Boniello, Bernd Nidetzky,