| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10235914 | Process Biochemistry | 2012 | 7 Pages |
Abstract
⺠EPA is an Ï3 polyunsaturated fatty acid beneficial to human health. ⺠Microorganisms provide an alternative source for this essential fatty acid. ⺠This review presents the de novo biosynthetic pathway for EPA in microorganisms. ⺠Metabolic engineering strategies to improve EPA productivity are also discussed.
Keywords
EPAβ-ketoacyl-ACP reductaseβ-ketoacyl-ACP synthaseETRAETADGLAPKSCOAGLAALAACPFASEDASDAγ-linolenic aciddihomo-γ-linolenic acidα-linolenic acidArachidonic acidStearic acidStearidonic acidOleic acidEicosadienoic acidEicosatetraenoic acidEicosapentaenoic acidEicosatrienoic aciddocosahexaenoic acidLinoleic acidfatty acid synthasePolyunsaturated fatty acidPUFABiosynthesisDHAEnoyl reductasePolyketide synthaseMetabolic engineeringacyl carrier proteincoenzyme A
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Yujin Cao, Yugang Cao, Min'an Zhao,