Article ID Journal Published Year Pages File Type
10267098 Electrochemistry Communications 2005 4 Pages PDF
Abstract
The electrochemical reduction of 4′-demicarosyl-10-hydro-11-dehydro-11-hydroxyimino-9-carbonyl-9-nor-8a,9seco-8a-aza-8a-homorelomycin was investigated by cyclic voltammetry and preparative scale electrolysis. It has been found that oxime group is reduced by ECEC mechanism in a four-electron process. The resulting products of the reduction consisted of the corresponding α,β-unsaturated amine and α,β-saturated ketone. The rate determining step was identified to be the cleavage of N-O bond. In the acidic media the actual leaving group is water and in neutral and moderate basic media hydroxyde ion.
Related Topics
Physical Sciences and Engineering Chemical Engineering Chemical Engineering (General)
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