Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10267098 | Electrochemistry Communications | 2005 | 4 Pages |
Abstract
The electrochemical reduction of 4â²-demicarosyl-10-hydro-11-dehydro-11-hydroxyimino-9-carbonyl-9-nor-8a,9seco-8a-aza-8a-homorelomycin was investigated by cyclic voltammetry and preparative scale electrolysis. It has been found that oxime group is reduced by ECEC mechanism in a four-electron process. The resulting products of the reduction consisted of the corresponding α,β-unsaturated amine and α,β-saturated ketone. The rate determining step was identified to be the cleavage of N-O bond. In the acidic media the actual leaving group is water and in neutral and moderate basic media hydroxyde ion.
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Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Zoran MandiÄ, Nevenka Lopotar,