| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10308130 | Schizophrenia Research | 2005 | 12 Pages |
Abstract
The finding of intact hemispheric specialization in ventrolateral PFC suggests that patients employ the same domain-specific strategies as healthy subjects during spatial and shape WM. Rather than reflecting a failure to adopt the optimal strategy, we hypothesize that WM deficits in schizophrenia reflect impairments of executive processes that are required for WM performance regardless of domain. These processes are associated with activity in the dorsolateral PFC, a region that has been repeatedly implicated in studies of WM.
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Authors
Dara S. Manoach, Nathan White, Kristen A. Lindgren, Stephan Heckers, Michael J. Coleman, Stéphanie Dubal, Donald C. Goff, Philip S. Holzman,