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Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress

Article ID Journal Published Year Pages File Type
10309126 Schizophrenia Research 2015 9 Pages PDF
Abstract
These results show that 5αR inhibition counters the PPI deficits induced by IR, possibly through limbic changes in pregnenolone and/or allopregnanolone concentrations.
Keywords
5α-reductaseneurosteroidsSchizophreniaPrepulse inhibitionIsolation rearingSensorimotor gating
Related Topics
Life Sciences Neuroscience Behavioral Neuroscience
Preview
Targeting neurosteroid synthesis as a therapy for schizophrenia-related alterations induced by early psychosocial stress
Authors
Roberto Frau, Federico Abbiati, Valentina Bini, Alberto Casti, Donatella Caruso, Paola Devoto, Marco Bortolato,
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Journal
Schizophrenia Research
Journal: Schizophrenia Research
Related Categories
5α-reductase
neurosteroids
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