Evaluation of a novel automated non-invasive pulse pressure variation algorithm

In mechanically ventilated patients, Pulse Pressure Variation (PPV) has been shown to be a useful parameter to guide fluid management. We evaluated a real-time automated PPV-algorithm by comparing it to manually calculated PPV-values. In 10 critically ill patients, blood pressure was measured invasively (IBP) and non-invasively (CNAP® Monitor, CNSystems Medizintechnik, Austria). PPV was determined manually and compared to automated PPV values: PPVmanIBP vs. PPVautoIBP was −0.19±1.65% (mean bias±standard deviation), PPVmanCNAP vs. PPVautoCNAP was −1.02±2.03% and PPVautoCNAP vs. PPVmanIBP was −2.10±3.14%, suggesting that the automated CNAP® PPV-algorithm works well on both blood pressure waveforms but needs further clinical evaluation.