Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10376399 | Journal of Colloid and Interface Science | 2012 | 7 Pages |
Abstract
⺠Double-encapsulation formulations were fabricated by incorporating liposomes as the W1 phase of W1/O/W2 double emulsions. ⺠Cryo-SEM images showed that liposomes are well encapsulated within the W1 phase. ⺠The release mechanism upon the freeze-thaw treatment is internal coalescence followed by external coalescence. ⺠The release of liposomes and FITC-BSA upon the freeze-thaw treatment is gradual rather than instant from the W1 phase. ⺠The release rate can be controlled by tuning the concentration of PC lipids in the liposomes.
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Authors
Qing Wang, Edith C. Rojas, Kyriakos D. Papadopoulos,