Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10376800 | Journal of Colloid and Interface Science | 2012 | 9 Pages |
Abstract
⺠Tailorable nanocarrier emulsion (TNE) prepared in simple sequential addition way. ⺠Auto-immune-relevant antigen coated onto emulsion stabilized by peptide surfactant. ⺠Lipophilic drug incorporated into the TNE enables auto-immune disease treatments. ⺠The TNE was internalized by model antigen-presenting cells. ⺠TNE uptake successfully downregulated the target protein (NF-κB) in macrophages.
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Authors
Yap Pang Chuan, Bi Yun Zeng, Brendan O'Sullivan, Ranjeny Thomas, Anton P.J. Middelberg,