| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10377213 | Journal of Colloid and Interface Science | 2011 | 9 Pages |
Abstract
⺠Novel nanodrugs based on protein-loaded polyelectrolyte complexes were produced. ⺠Nanodrug-model membrane interactions were studied with surface sensitive techniques. ⺠The nanodrugs collapsed into thin layers on top of oppositely charged lipid membranes. ⺠The bioreducible nanodrugs disintegrated when exposed to glutathione. ⺠The nanodrugs disintegrated when the ambient pH was reduced from 7.3 to 5.1.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
Rickard Frost, Gregory Coué, Johan F.J. Engbersen, Michael Zäch, Bengt Kasemo, Sofia Svedhem,