| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10377341 | Journal of Colloid and Interface Science | 2011 | 6 Pages |
Abstract
⺠First demonstration of separation of plasmid DNA isoforms using ultrafiltration. ⺠Novel separation mechanism based on differences in elongational flexibility. ⺠Separation characteristics very different than in SEC or agarose gels. ⺠Opportunities for large-scale purification of supercoiled isoform for gene therapy.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Colloid and Surface Chemistry
Authors
David R. Latulippe, Andrew L. Zydney,