Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10412899 | Sensors and Actuators B: Chemical | 2005 | 9 Pages |
Abstract
The design and the fabrication of an ion-selective electrode array platform aimed at in vitro intracellular recording are presented. The platform is composed of two parts: (i) a glass chip with microchannels whose bottom part is patterned with a platinum layer and (ii) a silicon chip in which an array of 50 μm long silicon nitride micropipettes with an inner diameter of 5 μm are structured. The 24 micropipettes are individually filled with a Ca2+ selective membrane, based on the neutral ionophore ETH 129. Preliminary tests in Ca2+ buffered solutions have shown a linear range from 10â6 to 0.1 M Ca2+ with a sensitivity of 27 mV/decade.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
O.T. Guenat, J.-F. Dufour, P.D. van der Wal, W.E. Morf, N.F. de Rooij, M. Koudelka-Hep,