Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10482116 | Physica A: Statistical Mechanics and its Applications | 2012 | 13 Pages |
Abstract
⺠Tumor evolution under therapy is considered. ⺠Under Norton-Simon hypothesis the system may be bistable. ⺠Bounded noise nonlinearly affects tumor carrying capacity and drug pharmacodynamics. ⺠Fluctuations may cause the transition from a small equilibrium to a larger one. ⺠A new and non-genetic kind of resistance to chemotherapy.
Related Topics
Physical Sciences and Engineering
Mathematics
Mathematical Physics
Authors
Alberto d'Onofrio, Alberto Gandolfi, Sara Gattoni,